Atreon 1g (Injection)
Manufactured by: Square Pharmaceuticals Ltd.
Aztreonam Similar medicine
Atreon is indicated for
- Cystic fibrosis
- Peritonitis
- Bacterial infections
- UTI
- Lower Respiratory Tract Infections
- Cystitis
- Gonorrhoea
- Septicemia
- Skin
- Skin-Structure Infections
- Endometritis
- Pelvic cellulitis
Precautions and warnings
Hypersensitivity to other beta-lactams, renal, pregnant women and hepatic impairment.
Side-effects
- IV: Phloebitis
- thrombophloebitis. IM: Pain
- swelling at inj site; diarrhoea
- nausea
- vomiting
- altered taste; jaundice
- hepatitis
- high liver enzymes; long prothrombin time
- partial thromboplastin time; rash
- urticaria
- eosinophilia. Potentially Fatal: Thrombocytopenia
- neutropenia; overgrowth of susceptible organisms; pseudomembranous colitis.
Drug Interactions
Concurrent use with oral anticoagulants may increase prothrombin time.
Contraindications
Hypersensitivity of lactation.
Mode of actions
Aztreonam has a high affinity for gram-negative bacteria's penicillin-binding protein 3 (PBP-3) and so has a bactericidal effect by blocking bacterial cell wall formation. It is very resistant to lactamase hydrolysis. Enterobacteriaceae spp, E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella, and Yersinia spp are all susceptible.
Dosage & Administration
Adult: IV/IM Gm-ve infections 1-8 g/day in divided doses depending on severity. Max: 8 g/day.
UTI 0.5-1 g 8-12 hrly.
IM Cystitis; Gonorrhoea 1 g as a single dose.
Child: and infants >1 wk: 30 mg/kg every 6 or 8 hr; >2 yr: 50 mg/kg every 6 or 8 hr for severe infections. Dose may be given via deep IM inj or slow IV inj or infusion. Doses >1 g should be given via IV route. Max (>2 yr): 8 g/day.
Renal impairment: Moderate to severe impairment: Same initial doses, adjust maintenance doses according to the patient's CrCl. Haemodialysis: A supplementary dose of 1/8 of the initial dose may be given after each session.
CrCl (ml/min)
10-30 Maintenance dose: Half of initial dose.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
There is no specific information about whether this medicine is passed on to the baby through breast milk. Discuss with your doctor before breastfeeding.
Pack Size & Price
1's pack Price : ৳450
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
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