Atreon 1g (Injection)
Manufactured by: Square Pharmaceuticals Ltd.
Aztreonam Similar medicine
Atreon is indicated for
- Mukoviszidose
- Peritonitis
- bakterielle Infektionen
- Harnwegsinfektionen
- Infektionen der unteren Atemwege
- Zystitis
- Gonorrhoe
- Septikämie
- Haut- und Hautstrukturinfektionen
- Endometritis
- Beckenzellulitis
Precautions and warnings
Überempfindlichkeit gegen andere Beta-Lactame, Nieren-, Schwangeren- und Leberfunktionsstörung.
Side-effects
- IV: Phloebitis und Thrombophloebitis. IM: Schmerzen und Schwellung an der Injektionsstelle; Durchfall
- Übelkeit
- Erbrechen
- veränderter Geschmack; Gelbsucht
- Hepatitis
- hohe Leberenzyme; lange Prothrombinzeit
- partielle Thromboplastinzeit; Hautausschlag
- Urtikaria
- Eosinophilie. Potenziell tödlich: Thrombozytopenie
- Neutropenie; Überwucherung anfälliger Organismen; pseudomembranöse Kolitis.
Drug Interactions
Die gleichzeitige Anwendung mit oralen Antikoagulanzien kann die Prothrombinzeit verlängern.
Contraindications
Überempfindlichkeit der Laktation.
Mode of actions
Aztreonam hat eine hohe Affinität zum Penicillin-bindenden Protein 3 (PBP-3) gramnegativer Bakterien und hat daher eine bakterizide Wirkung, indem es die Bildung von Bakterienzellwänden blockiert. Es ist sehr resistent gegen Lactamase-Hydrolyse. Enterobacteriaceae spp, E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella und Yersinia spp sind alle anfällig.
Dosage & Administration
Erwachsene: IV/IM Gm-ve-Infektionen 1–8 g/Tag in aufgeteilten Dosen je nach Schweregrad. Maximal: 8 g/Tag.
Harnwegsinfekt 0,5–1 g 8–12 Stunden.
IM-Zystitis; Gonorrhoe 1 g als Einzeldosis.
Kinder: und Säuglinge > 1 Woche: 30 mg/kg alle 6 oder 8 Stunden; >2 Jahre: 50 mg/kg alle 6 oder 8 Stunden bei schweren Infektionen. Die Dosis kann durch tiefe i.m.-Injektion oder langsame i.v.-Injektion oder Infusion verabreicht werden. Dosen >1 g sollten intravenös verabreicht werden. Maximal (>2 Jahre): 8 g/Tag.
Nierenfunktionsstörung: Mäßige bis schwere Beeinträchtigung: Gleiche Anfangsdosen, Erhaltungsdosen entsprechend der CrCl des Patienten anpassen. Hämodialyse: Nach jeder Sitzung kann eine zusätzliche Dosis von 1/8 der Anfangsdosis verabreicht werden.
CrCl (ml/min)
10-30 Erhaltungsdosis: Die Hälfte der Anfangsdosis.
Pregnancy & Lactation
Obwohl tierexperimentelle Reproduktionsstudien eine nachteilige Wirkung gezeigt haben, konnte das Risiko für den Fötus manchmal nicht nachgewiesen werden, und es gibt keine ausreichenden und gut kontrollierten Studien bei schwangeren Frauen. Während der Schwangerschaft kann dieses Arzneimittel jedoch nur dann angewendet werden, wenn dies unbedingt erforderlich ist.
Besprechen Sie dies mit Ihren Ärzten und teilen Sie ihnen Feedback zu diesem Arzneimittel mit.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel über die Muttermilch auf das Baby übertragen wird. Besprechen Sie dies mit Ihrem Arzt, bevor Sie stillen.
Pack Size & Price
1's pack Price : ৳450
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
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