Atreon 1g (Injection)
Manufactured by: Square Pharmaceuticals Ltd.
Aztreonam Similar medicine
Atreon is indicated for
- Fibrose cística
- peritonite
- infecções bacterianas
- ITU
- infecções do trato respiratório inferior
- cistite
- gonorreia
- septicemia
- infecções da pele e da estrutura da pele
- endometrite
- celulite pélvica
Precautions and warnings
Hipersensibilidade a outros beta-lactâmicos, insuficiência renal, gestantes e insuficiência hepática.
Side-effects
- IV: Floebite e tromboflebite. IM: Dor e inchaço no local da lesão; diarreia
- náuseas
- vómitos
- alteração do paladar; icterícia
- hepatite
- enzimas hepáticas elevadas; tempo de protrombina longo
- tempo de tromboplastina parcial; erupção cutânea
- urticária
- eosinofilia. Potencialmente Fatal: Trombocitopenia
- neutropenia; crescimento excessivo de organismos suscetíveis; colite pseudomembranosa.
Drug Interactions
O uso concomitante com anticoagulantes orais pode aumentar o tempo de protrombina.
Contraindications
Hipersensibilidade da lactação.
Mode of actions
O aztreonam tem uma alta afinidade pela proteína 3 de ligação à penicilina (PBP-3) de bactérias gram-negativas e, portanto, tem um efeito bactericida ao bloquear a formação da parede celular bacteriana. É muito resistente à hidrólise da lactamase. Enterobacteriaceae spp, E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella e Yersinia spp são todas suscetíveis.
Dosage & Administration
Adulto: Infecções Gm-ve IV/IM 1-8 g/dia em doses divididas dependendo da gravidade. Máx.: 8 g/dia.
ITU 0,5-1 g 8-12 horas.
Cistite primária; Gonorreia 1 g em dose única.
Criança: e bebês >1 semana: 30 mg/kg a cada 6 ou 8 horas; >2 anos: 50 mg/kg a cada 6 ou 8 horas para infecções graves. A dose pode ser administrada por injeção IM profunda ou injeção IV lenta ou infusão. Doses >1 g devem ser administradas por via intravenosa. Máx. (>2 anos): 8 g/dia.
Insuficiência renal: Insuficiência moderada a grave: Mesmas doses iniciais, ajustar as doses de manutenção de acordo com a CrCl do paciente. Hemodiálise: Uma dose suplementar de 1/8 da dose inicial pode ser administrada após cada sessão.
CrCl (ml/min)
10-30 Dose de manutenção: Metade da dose inicial.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
1's pack Price : ৳450
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
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