Sural 400mg (Tablet)
Manufactured by: Ambee Pharmaceuticals Ltd.
Ethambutol Similar medicine
Sural is indicated for
- Tuberculosis
Precautions and warnings
People who have poor vision before starting treatment, as well as elderly people and children, need special care. Regularly check liver and kidney function, as well as eyesight. Be careful when checking vision in patients with cataracts, diabetes, or repeated eye inflammation to ensure any vision changes are not caused by their existing conditions.
Side-effects
- Retrobulbar neuritis with a reduction in visual acuity
- constriction of visual field
- central or peripheral scotoma
- green-red colour blindness. Retinal haemorrhage (rare); reduced renal clearance of urates (acute gout); GI disturbances eg
- nausea
- vomiting
- abdominal pain
- anorexia; rash
- headache
- dizziness
- confusion
- hallucinations
- malaise
- jaundice; thrombocytopenia; pulmonary infiltrates.
Mode of actions
Ethambutol works by blocking RNA production, which stops Mycobacteria from multiplying. It slows down the growth of M. tuberculosis, especially the fast-growing bacteria found in lung cavity walls, but it also works against slower-growing bacteria. Ethambutol can also help fight other types of Mycobacteria, like M. kansasii and the Mycobacterium avium complex (MAC), which are sometimes seen in people with weakened immune systems.
Dosage & Administration
Oral
Primary treatment of pulmonary and extrapulmonary tuberculosis
Adult: As hydrochloride: Initial 8 wk: 15 mg/kg/day or 30 mg/kg thrice wkly given with isoniazid, rifampicin and pyrazinamide. For patients with history of antimycobacterial therapy: Initial doses: 25 mg/kg/day for 60 days, thereafter reduce to 15 mg/kg/day.
Child: For treatment of drug-resistant tuberculosis: 15-25 mg/kg daily or 50 mg/kg twice wkly. For congenitally acquired tuberculosis: Neonates: 15 mg/kg once daily and >1 mth: 15 mg/kg once daily or 30 mg/kg 3 times wkly for 2 mth initial treatment phase.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
100's pack Price : ৳166
Similar medicine
Manufactured by: Sanofi Aventis (BD) Ltd.
Manufactured by: Ambee Pharmaceuticals Ltd.
Manufactured by: Novartis (Bangladesh) Ltd.
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