Atreon 2g (Injection)
Manufactured by: Square Pharmaceuticals Ltd.
Aztreonam Similar medicine
Atreon is indicated for
- Муковисцидоз
- перитонит
- бактериальные инфекции
- ИМП
- инфекции нижних дыхательных путей
- цистит
- гонорея
- септицемия
- инфекции кожи и кожных структур
- эндометрит
- тазовый целлюлит
Precautions and warnings
Повышенная чувствительность к другим бета-лактамам, нарушение функции почек, беременных и печени.
Side-effects
- IV: Флебит и тромбофлебит. IM: Боль и припухлость в месте инъекции; диарея
- тошнота
- рвота
- изменение вкуса; желтуха
- гепатит
- повышение активности печеночных ферментов; длительное протромбиновое время
- частичное тромбопластиновое время; сыпь
- крапивница
- эозинофилия. Потенциально смертельно: тромбоцитопения
- нейтропения; чрезмерный рост восприимчивых организмов; псевдомембранозный колит.
Drug Interactions
Одновременное применение с пероральными антикоагулянтами может увеличить протромбиновое время.
Contraindications
Гиперчувствительность в период лактации.
Mode of actions
Азтреонам обладает высоким сродством к пенициллинсвязывающему белку 3 грамотрицательных бактерий (PBP-3) и поэтому оказывает бактерицидное действие, блокируя образование клеточной стенки бактерий. Он очень устойчив к гидролизу лактамазами. Восприимчивы виды Enterobacteriaceae, E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella и Yersinia.
Dosage & Administration
Взрослые: внутривенно/в/м при инфекциях Gm-ve 1–8 г/день в несколько приемов в зависимости от тяжести заболевания. Макс: 8 г/день.
ИМВП 0,5–1 г каждые 8–12 часов.
в/м цистит; Гонорея 1 г однократно.
Дети: и младенцы старше 1 недели: 30 мг/кг каждые 6 или 8 часов; >2 лет: 50 мг/кг каждые 6 или 8 часов при тяжелых инфекциях. Дозу можно вводить посредством глубокой внутримышечной инъекции, медленной внутривенной инъекции или инфузии. Дозы >1 г следует вводить внутривенно. Макс (>2 лет): 8 г/день.
Нарушение функции почек: Нарушение от умеренной до тяжелой степени: начальные дозы те же, поддерживающие дозы корректируются в соответствии с CrCl пациента. Гемодиализ: после каждого сеанса может вводиться дополнительная доза в размере 1/8 начальной дозы.
CrCl (мл/мин)
10–30 Поддерживающая доза: половина начальной дозы.
Pregnancy & Lactation
Хотя исследования на репродукции животных показали неблагоприятное воздействие, иногда даже неспособное продемонстрировать риск для плода, а адекватных и хорошо контролируемых исследований у беременных женщин нет, во время беременности это лекарство можно применять только тогда, когда это определенно необходимо.
Обсудите это со своими врачами и расскажите им отзывы об этом лекарстве.
Нет конкретной информации о том, передается ли это лекарство ребенку через грудное молоко. Перед кормлением грудью обсудите это с врачом.
Pack Size & Price
1's pack Price : ৳650
Similar medicine
Manufactured by: Incepta Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
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