Maxipen IV 500 mg + 500 mg (IM/IV Injection)
Manufactured by: Opsonin Pharma Limited
Cilastatin + Imipenem Similar medicine
Maxipen IV is indicated for
- Fibrose cística
- septicemia bacteriana
- endocardite
- infecções suscetíveis
- infecções do trato respiratório inferior
- gonorréia
- infecções da pele e da estrutura da pele
- infecções do trato urinário
- infecções ósseas e articulares
- profilaxia cirúrgica
Precautions and warnings
Tenha cuidado ao administrar este medicamento a pacientes alérgicos a outros antibióticos beta-lactâmicos, pois eles também podem reagir a este medicamento. Use com cautela em pessoas com doenças como epilepsia ou problemas renais ou hepáticos. Tome cuidado extra se a paciente estiver grávida ou amamentando.
Side-effects
- Erupções cutâneas
- urticária
- eosinofilia
- febre
- náuseas
- vómitos
- diarreia
- descoloração dos dentes ou da língua e alteração do paladar. Eritema multiforme
- dermatite esfoliativa. Dor e tromboflebite podem ocorrer no local da lesão. Potencialmente fatal: síndrome de Stevens-Johnson
- necrólise epidérmica tóxica.
Drug Interactions
Tomar probenecida ao mesmo tempo que a cilastatina pode fazer com que a cilastatina permaneça no corpo por mais tempo. O uso de cilastatina junto com ganciclovir pode aumentar o risco de convulsões.
Mode of actions
O imipenem é um antibiótico forte que mata muitos tipos de bactérias, impedindo-as de construir as suas paredes celulares. Funciona bem porque não é decomposto por certas enzimas (chamadas ?-lactamases) que muitas bactérias utilizam para se protegerem. A cilastatina é um medicamento que bloqueia uma enzima nos rins (chamada desidropeptidase I). Quando o imipenem é administrado juntamente com a cilastatina, ajuda a prevenir a degradação do imipenem nos rins e protege contra danos renais. Ambas as drogas são administradas como sais de sódio.
Dosage & Administration
Adulto: IV Infecções suscetíveis Como imipenem: 1-2 g/dia em doses divididas de 6 a 8 horas. Profilaxia cirúrgica Como imipenem: 1 g na indução da anestesia, seguido de 1 g 3 horas depois. Doses adicionais de 500 mg podem ser administradas 8 e 16 horas após a indução, se necessário.
Criança: >40 kg: igual à dose para adulto. >3 meses e
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
As mães com um bebê recém-nascido que usaram este medicamento durante os últimos 3 meses de gravidez raramente podem apresentar sintomas incluindo sonolência, rigidez ou tremores musculares, problemas de alimentação ou respiração, choro constante. Se você notar algum destes sintomas em seu bebê, especialmente durante o primeiro mês, informe o médico imediatamente.
Este medicamento passa para o leite materno. Converse com seu médico antes de amamentar.
Pack Size & Price
Price : ৳
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