Flocet IV 200mg/100ml (Infusion)
Manufactured by: Opsonin Pharma Limited
Ofloxacin Similar medicine
Flocet IV is indicated for
- Kusta
- bronkitis kronis; Pneumonia yang didapat dari komunitas; Infeksi kulit tanpa komplikasi
- antraks
- penyakit Legionnaire
- servisitis nongonokokus; Uretritis
- Sistitis tanpa komplikasi
- ISK dengan komplikasi
- Diare saat bepergian
- prostatitis akibat bakteri
- Demam tifoid
- Infeksi kulit dan jaringan lunak
- Gonore tanpa komplikasi
- Penyakit radang panggul
- Infeksi saluran pernapasan bawah
- Septikemia
Precautions and warnings
Orang dengan epilepsi atau kecenderungan untuk mengalami kejang, mereka yang mengetahui atau mencurigai adanya masalah dengan sistem saraf pusat, masalah ginjal atau hati, miastenia gravis, atau berisiko terkena infeksi sekunder (superinfeksi), serta anak-anak, harus berhati-hati.
Side-effects
- Mual
- muntah
- sakit perut
- diare; sakit kepala
- pusing
- susah tidur
- halusinasi; leukopenia dan eosinofilia; radang vagina; dysgeusia; kerusakan dan pecahnya tendon; anoreksia; getaran; fotosensitifitas; reaksi hipersensitivitas. Hentikan jika terjadi reaksi psikiatrik
- neurologis
- atau hipersensitivitas. Berpotensi Fatal: Anafilaksis; jarang kejang.
Drug Interactions
Mengonsumsi obat antiaritmia tertentu dari kelas IA (seperti quinidine, procainamide) atau kelas III (seperti amiodarone, sotalol) secara bersamaan dapat meningkatkan risiko irama jantung yang berbahaya (perpanjangan interval QT). Antasida yang mengandung magnesium, aluminium, atau kalsium dapat menurunkan jumlah obat dalam darah dan urin Anda. Jika dikonsumsi dengan antibiotik aminoglikosida (seperti amikasin, tobramycin), mungkin terdapat efek antibakteri yang lebih kuat. Penggunaan kortikosteroid secara bersamaan dapat meningkatkan risiko masalah tendon yang serius. NSAID dapat meningkatkan risiko efek samping sistem saraf, seperti kejang. Mengonsumsi obat ini dengan teofilin dapat menyebabkan kadar teofilin yang lebih tinggi dan bertahan lebih lama dalam darah Anda, sehingga meningkatkan risiko efek samping dari teofilin.
Contraindications
Jangan gunakan jika Anda alergi terhadap kuinolon, sedang hamil atau menyusui, memiliki interval QT yang berkepanjangan, atau memiliki kadar kalium rendah yang tidak diobati (hipokalemia).
Mode of actions
Ofloxacin adalah sejenis antibiotik fluoroquinolone yang bekerja dengan cara memblokir enzim bakteri yang disebut topoisomerase IV dan DNA girase, yang diperlukan bakteri untuk menyalin, memperbaiki, dan memproduksi DNA mereka. Hal ini membuatnya efektif melawan berbagai jenis bakteri gram negatif dan gram positif.
Dosage & Administration
Dewasa: PO Bagian dari terapi multiobat pada kusta 400 mg/hari atau sebentar-sebentar, tergantung regimen. Gonore tanpa komplikasi Dosis tunggal 400 mg. Eksaserbasi bakteri akut pada bronkitis kronis;
Pneumonia yang didapat dari komunitas; Infeksi kulit tanpa komplikasi 400 mg dua kali sehari selama 10 hari. Penyakit radang panggul 400 mg dua kali sehari selama 14 hari. Profilaksis pasca pajanan setelah pajanan antraks inhalasi 400 mg dua kali sehari selama 60 hari.
Penyakit Legionnaire 400 mg dua kali sehari selama 2-3 minggu. Infeksi campuran pada uretra dan leher rahim akibat C. trachomatis dan Neisseria gonorrhoeae; servisitis nongonokokus; Uretritis akibat Chlamydia trachomatis 200-300 mg dua kali sehari selama 7 hari.
Sistitis tanpa komplikasi 200 mg dua kali sehari selama 3-7 hari. Durasi tergantung pada agen penyebab. ISK dengan komplikasi 200 mg dua kali sehari selama 10 hari. Diare pelancong 300 mg dua kali sehari selama 1-3 hari. Prostatis bakteri kronis 300 mg dua kali sehari selama 6 minggu. Demam tifoid 200-400 mg dua kali sehari selama 7-14 hari.
Intravena
Dewasa: 200 mg setiap hari melalui infus IV selama minimal 30 menit. Maks: 400 mg dua kali sehari diinfuskan selama minimal 1 jam.
Gangguan ginjal: Dosis awal seperti biasa kemudian dikurangi.
CrCl (ml/menit)
20-50 Kurangi dosis hingga setengahnya atau berikan dosis biasa setiap 24 jam.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
100ml bot Price : ৳
Similar medicine
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Square Pharmaceuticals Ltd.
Manufactured by: Opsonin Pharma Limited
Manufactured by: Opsonin Pharma Limited
Manufactured by: Opsonin Pharma Limited
Manufactured by: Drug International Ltd.
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