Lamisil 250mg (Tablet)
Manufactured by: Novartis (Bangladesh) Ltd.
Terbinafine Similar medicine
Lamisil is indicated for
- Kurap pada kaki
- Kurap pada tungkai
- Kurap pada tubuh
- Dermatofitosis
- Infeksi kuku
Precautions and warnings
Jika Anda memiliki masalah hati atau ginjal, atau jika Anda sedang hamil, diperlukan perawatan khusus. Pastikan fungsi hati Anda diuji sebelum memulai pengobatan oral.
Side-effects
- Anoreksia
- mual
- sakit perut
- gangguan pengecapan
- diare
- ruam
- urtikaria. Berpotensi Fatal: Gagal hati
- sindrom Stevens-Johnson
- neutropaenia.
Drug Interactions
Obat yang dipecah oleh enzim CYP450 2D6 mungkin memiliki kadar yang lebih tinggi bila dikonsumsi dengan terbinafine. Rifampisin dapat menurunkan jumlah terbinafin dalam tubuh, sedangkan simetidin dapat meningkatkan kadar terbinafin.
Contraindications
Hipersensitivitas, penyakit hati aktif atau kronis, laktasi.
Mode of actions
Terbinafine bekerja dengan memblokir squalene epoxidase, enzim penting yang dibutuhkan jamur untuk membuat sterol untuk dinding selnya. Hal ini mencegah jamur memproduksi ergosterol, komponen kunci dinding selnya, yang menyebabkan kematian sel jamur. Terbinafine efektif membunuh dermatofita (sejenis jamur penyebab infeksi kulit) dan beberapa jenis jamur.
Dosage & Administration
Lisan
Dermatofitosis
Dewasa: 250 mg sekali sehari selama 2-4 minggu pada tinea kruris, 6 minggu untuk tinea pedis, 4 minggu untuk tinea corporis, dan 6-12 minggu untuk infeksi kuku.
Anak: 10-20 kg: 62,5 mg; 20-40kg: 125mg; >40kg: 250mg. Dosis diminum sekali sehari. Pengobatan biasanya diberikan selama 2 minggu untuk tinea capitis; 2-4 minggu untuk tinea cruris; 4 minggu untuk tinea corporis; 6 minggu di tinea pedis; 6-12 minggu untuk infeksi kuku.
Gangguan ginjal:
CrCl (ml/menit)
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan telah menunjukkan efek buruk bahkan terkadang tidak dapat menunjukkan risiko pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan hanya jika benar-benar diperlukan.
Diskusikan dengan dokter Anda dan beri tahu mereka tanggapan tentang obat ini.
Belum ada informasi spesifik apakah obat ini ditularkan ke bayi melalui ASI. Diskusikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
14's pack Price : ৳2030
Similar medicine
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