Lamisil 250mg (Tablet)
Manufactured by: Novartis (Bangladesh) Ltd.
Terbinafine Similar medicine
Lamisil is indicated for
- Micose do pé
- Micose da perna
- Micose do corpo
- Dermatofitose
- Infecções nas unhas
Precautions and warnings
Se você já tiver problemas de fígado ou rins, ou se estiver grávida, são necessários cuidados especiais. Certifique-se de testar sua função hepática antes de iniciar o tratamento oral.
Side-effects
- Anorexia
- náusea
- dor abdominal
- alterações do paladar
- diarreia
- erupção cutânea
- urticária. Potencialmente fatal: insuficiência hepática
- síndrome de Stevens-Johnson
- neutropenia.
Drug Interactions
Os medicamentos que são decompostos pela enzima CYP450 2D6 podem apresentar níveis mais elevados quando tomados com terbinafina. A rifampicina pode diminuir a quantidade de terbinafina no corpo, enquanto a cimetidina pode aumentar os níveis de terbinafina.
Contraindications
Hipersensibilidade, doença hepática ativa ou crônica, lactação.
Mode of actions
A terbinafina atua bloqueando a esqualeno epoxidase, uma enzima importante que os fungos precisam para produzir esteróis para suas paredes celulares. Isto impede que o fungo produza ergosterol, um componente chave da sua parede celular, levando à morte das células fúngicas. A terbinafina é eficaz na eliminação de dermatófitos (um tipo de fungo que causa infecções na pele) e alguns tipos de leveduras.
Dosage & Administration
Oral
Dermatofitose
Adulto: 250 mg uma vez ao dia durante 2-4 semanas para tinea cruris, 6 semanas para tinea pedis, 4 semanas para tinea corporis e 6-12 semanas para infecções ungueais.
Criança: 10-20 kg: 62,5 mg; 20-40kg: 125mg; >40 kg: 250 mg. Doses a serem tomadas uma vez ao dia. O tratamento geralmente é administrado por 2 semanas para tinea capitis; 2-4 semanas para tinea cruris; 4 semanas para tinea corporis; 6 semanas em tinea pedis; 6-12 semanas para infecções nas unhas.
Insuficiência renal:
CrCl (ml/min)
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso, mesmo por vezes incapaz de demonstrar o risco para o feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário.
Discuta com seus médicos e dê-lhes comentários sobre este medicamento.
Não há informações específicas sobre se este medicamento é transmitido ao bebê através do leite materno. Discuta com seu médico antes de amamentar.
Pack Size & Price
14's pack Price : ৳2030
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