Amifen 250mg (Tablet)
Manufactured by: Opsonin Pharma Limited
Mefenamic Acid Similar medicine
Amifen is indicated for
- Rheumatoid arthritis
- Osteoarthritis
- Dysmenorrhoea
- Menorrhagia
- Dental pain
- Pain
- inflammation
- Mild to moderate pain
- Postoperative pain
Precautions and warnings
Kidney or liver problems, and asthma: Use with caution. For long-term use, regularly check blood counts and liver function. This medicine may cause drowsiness, which can affect your ability to do tasks that require skill. Be especially careful in older adults.
Side-effects
- Abdominal pain
- dyspepsia
- constipation
- diarrhoea
- nausea
- GI ulcers; oedema; bronchospasm; headache
- drowsiness
- insomnia
- visual disturbances; CHF
- hypertension
- tachycardia
- syncope; urticaria
- rash; thrombocytopenia
- aplastic anaemia
- agranulocytosis; tinnitus; elevated liver enzymes; abnormal renal function. Potentially Fatal: Autoimmune haemolytic anaemia; convulsions (overdosage).
Drug Interactions
Taking mefenamic acid together with drugs that block the CYP2C9 enzyme can change how safe or effective it is. It can also increase the harmful effects of methotrexate. Mefenamic acid may make ACE inhibitors or angiotensin II receptor blockers less effective in lowering blood pressure. The risk of serious stomach problems is higher if taken with aspirin. Mefenamic acid may reduce how well furosemide or thiazide diuretics help the body get rid of salt. It can also cause lithium to build up in the blood by reducing how quickly the kidneys remove it. Lastly, taking it with warfarin may increase the risk of bleeding.
Contraindications
Not recommended for people with inflammatory bowel disease, peptic ulcers, newborn babies, or women in the third trimester of pregnancy or who are breastfeeding. Also should not be used by those who have had coronary artery bypass graft surgery, severe kidney problems, or severe heart failure.
Mode of actions
**Uses:**
- Rheumatoid arthritis
- Mild to moderate pain
- Dental pain
- Postoperative pain (after surgery)
- Period pain (dysmenorrhoea)
- Osteoarthritis
- Heavy menstrual bleeding (menorrhagia)
**Dosage:**
- **Adults:** 500 mg three times a day (tid).
- **Children (older than 6 months):** 25 mg per kg of body weight, divided into several doses throughout the day, for up to 7 days.
Dosage & Administration
Oral
Rheumatoid arthritis, Mild to moderate pain, Dental pain, Postoperative pain, Dysmenorrhoea, Osteoarthritis, Menorrhagia
Adult: 500 mg tid.
Child: >6 mth 25 mg/kg daily in divided doses for up to 7 days.
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
100's pack Price : ৳280
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There are few similar medicines of Amifen are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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