Amikacin IV/IM 500mg/2ml (Injection)
Manufactured by: Apex Pharmaceuticals Ltd.
Amikacin Similar medicine
Amikacin IV/IM is indicated for
- Tuberculosis
- Infecciones del tracto urinario complicadas y recurrentes
- Infecciones graves por gramnegativos
- Infecciones por micobacterias no tuberculosas
- Septicemia bacteriana
- Infecciones del tracto respiratorio
- Huesos y articulaciones
- Sistema nervioso central y piel y tejidos blandos
- Infecciones intraabdominales
- Quemaduras
- Infecciones postoperatorias
- Meningitis
- Peritonitis
- Sepsis neonatal
Precautions and warnings
El vértigo y el tinnitus son síntomas de insuficiencia renal. Si observa signos de ototoxicidad, neurotoxicidad o hipersensibilidad, deje de tomarlo; Si estás amamantando, deja de usarlo. No se ha demostrado que el período de tratamiento de andgt;14 días sea seguro. Antes y durante el tratamiento, controle la función de sus riñones.
Side-effects
- tinnitus
- vértigo; ataxia y sordera manifiesta. Potencialmente fatal: ototoxicidad
- nefrotoxicidad
- bloqueo neuromuscular.
Drug Interactions
Cuando se toma simultáneamente, la anfotericina B puede causar nefrotoxicidad y limitar el aclaramiento de amikacina.
Posiblemente letal: Otros medicamentos nefrotóxicos u ototóxicos tienen mayores efectos ototóxicos o nefrotóxicos. Los medicamentos bloqueadores neuromusculares mejoran el bloqueo neuromuscular. Los diuréticos potentes aumentan el riesgo de ototoxicidad.
Contraindications
Embarazo, perforación del tímpano, miastenia gravis, hipersensibilidad.
Mode of actions
La amikacina se une a las subunidades ribosómicas 30S de bacterias susceptibles, inhibiendo así su síntesis de proteínas.
Dosage & Administration
parenteral
Infecciones del tracto urinario no complicadas
Adultos: 250 mg dos veces al día, administrados por vía IM, IV durante 2-3 minutos o como infusión IV.
Infecciones graves por gramnegativos resistentes a gentamicina y tobramicina
Adultos: 15 mg/kg al día en dosis divididas equitativamente inyectadas cada 8 o 12 horas durante 7 a 10 días. Máx.: Hasta 500 mg cada 8 horas en infecciones potencialmente mortales. Dosis máxima acumulada: 15 g. Las dosis se pueden administrar por vía IM, inyección IV lenta durante 2-3 minutos o infusión IV.
Niños: 15 mg/kg al día en dosis iguales divididas, inyectadas cada 8 o 12 horas durante 7 a 10 días. Recién nacidos: 10 mg/kg al día en 2 dosis divididas.
Función renal alterada: En pacientes con función renal alterada se debe reducir la dosis diaria y/o aumentar los intervalos entre dosis para evitar la acumulación del fármaco. A continuación se detalla el esquema de dosis simple para la insuficiencia renal:
Función renal Pauta de dosificación
Deterioro leve 500 mg cada 18 horas
Insuficiencia moderada 500 mg cada 24 horas
Insuficiencia grave 250 mg cada 24 horas.
Pregnancy & Lactation
Este medicamento no está permitido durante el embarazo. No lo utilice si está embarazada. Puede absorberse a través de la piel y los pulmones y puede dañar los órganos del feto y provocar discapacidades congénitas. Control de la natalidad estricto y eficaz durante el tratamiento y durante seis meses después de suspender este medicamento. Si queda embarazada, deje de tomar este medicamento y hable con su médico de inmediato.
No existe información específica sobre si este medicamento pasa a la leche materna o no. Teniendo en cuenta los posibles riesgos para los niños, no se recomienda amamantar mientras se utiliza este medicamento y al menos dos semanas después de la última dosis. Consulte a su médico antes de amamantar.
Pack Size & Price
5's pack Price : ৳240
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