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Cortan 5mg/5ml (Solution)

Manufactured by: Incepta Pharmaceuticals Ltd.

Prednisolone Similar medicine

Cortan is indicated for

  • Rheumatoid arthritis
  • Multiple sclerosis
  • Allergic
  • inflammatory disorders
  • Nephrotic syndrome
  • Idiopathic thrombocytopenic purpura
  • Joint inflammations
  • Moderate to severe asthma
  • Infantile spasms

Precautions and warnings

Before taking this medication, tell your doctor or pharmacist if you have any of the following medical conditions: cataracts, glaucoma, high blood pressure, liver disease, kidney disease, thyroid problems, diabetes, stomach/intestinal problems (such as diverticulitis, ulcer), brittle bones (osteoporosis), current/past infections (such as tuberculosis, positive tuberculosis test, herpes, fungal), bleeding.

This medication has the potential to make you dizzy. You may become dizzy if you consume alcohol or marijuana (cannabis). Do not drive, operate machinery, or engage in any other activity that requires attentiveness until you are sure you can do so safely. Limit your intake of alcoholic beverages. If you use marijuana, talk to your doctor (cannabis).

This medication has the potential to induce stomach bleeding. While using this prescription, drinking alcohol on a regular basis may raise your risk of stomach bleeding. Limit your intake of alcoholic beverages. For more information, talk to your doctor or pharmacist.

Tell your doctor or dentist about all the products you consume before surgery (including prescription drugs, nonprescription drugs, and herbal products).

Alcohol, sugar, and aspartame may be present in this product. If you have diabetes, alcoholism, liver illness, phenylketonuria (PKU), or any other condition that requires you to limit or avoid these chemicals in your diet, proceed with caution. Consult your doctor for advice on how to use this medicine safely.

Long-term use of corticosteroid drugs can make it harder for your body to respond to physical stress. Tell your doctor if you are using or have taken this medicine within the last 12 months before undergoing surgery or emergency treatment, or if you acquire a major illness. If you experience unusual exhaustion or weight loss, contact your doctor right away.

This drug has the potential to conceal signs of infection. It may increase your risk of infection or worsen any present infections. Avoid coming into contact with somebody who has an infection that could transmit to others such as chickenpox, measles, flu. If you think you've been exposed to an infection or want further information, talk to your doctor.

Before getting any vaccines or vaccinations, inform your doctor that you are taking prednisolone. Contact with people who have just received live vaccinations should be avoided such as flu vaccine inhaled through the nose.

If used for an extended period of time, this medicine may slow down a child's growth. For more information, talk to your doctor or pharmacist. Regularly see the doctor to have your child's height and growth measured.

The effects of this medicine, including bone pain, stomach/intestinal bleeding, and mental/mood disorders, may be more pronounced in older persons such as confusion.

Side-effects

  • Cushing's syndrome
  • growth retardation in childn; osteoporosis
  • fractures. Peptic ulceration; glaucoma
  • cataracts; hyperglycaemia
  • pancreatitis; increased appetite
  • obesity. Potentially Fatal: Acute adrenal insufficiency precipitated by infection
  • trauma or surgery in patients on long-term therapy or following cessation of such therapy. CV collapse following rapid IV injection.

Drug Interactions

Other drugs may interfere with the elimination of prednisolone from your body (such as antiplatelet drugs like clopidogrel, "blood thinners" like dabigatran/warfarin, and NSAIDs like aspirin/celecoxib/ibuprofen).

If your doctor has prescribed low-dose aspirin (typically 81-162 mg per day) for heart attack or stroke prevention, you should stick to it unless your doctor tells you differently. For more information, consult your doctor or pharmacist.

Contraindications

Patient with Live vaccines, herpes simplex keratitis, systemic infections should needed extra care.

Mode of actions

Prednisolone reduces inflammation by stopping polymorphonuclear leukocytes from migrating and reversing enhanced capillary permeability. It lowers the immune system by lowering lymphocyte and eosinophil activity and generation.

Dosage & Administration

Oral
Allergic and inflammatory disorders
Adult: 5-60 mg daily in 2-4 divided doses. Maintenance: 2.5-15 mg daily. Withdrawal should be gradual after long-term therapy.

Child: 1 mth-18 yr: Autoimmune inflammatory disorders: Initially, 1-2 mg/kg once daily; may reduce dose gradually after a few days if needed. Max: 60 mg daily. Autoimmune hepatitis: Initially, 2 mg/kg once daily, then reduce to minimum effective dose. Max: 40 mg daily.

Poorly controlled, moderate to severe asthma
Adult: Patients with at least 2 exacerbations/yr requiring oral corticosteroids: 40-60 mg daily in 1-2 divided doses; usually given as a short course treatment over 3-10 days until symptom resolution and patient achieves a peak expiratory flow (PEF) of at least 80% of his or her personal best. May be used with maintenance dosages of inhaled corticosteroid and a long-acting inhaled ?2-agonist bronchodilator.

Child: Patients with >3 exacerbations/yr in children ?4 yr or at least 2 exacerbations/yr in children 5-11 yr: 1-2 mg/kg daily for 3-5 days may be used with existing asthma treatment; dose may be given in 1-2 divided doses. Max: 60 mg daily.

Nephrotic syndrome
Child: 1 mth-18 yr: Initially, 60 mg/m2 (max: 80 mg) once daily for 4 wk until urine is protein-free followed by 40 mg/m2 every other day for 4 wk, then withdraw dose gradually. Prevention of relapse: 0.5-1 mg/kg once daily every other day for 3-6 mth.

Rheumatoid arthritis
Adult: Initially, 5-7.5 mg daily, adjusted as necessary.
Elderly: 5 mg daily.

Multiple sclerosis
Adult: 200 mg daily for 1 wk followed by 80 mg every other day for 1 mth.

Infantile spasms
Child: 1 mth-2 yr: Initially, 10 mg 4 times daily for 14 days; increase to 20 mg 3 times daily for 7 days if seizures are not controlled after 7 days; reduce dose slowly over 15 days until therapy is stopped. For patients taking 40 mg daily, reduce dose in steps of 10 mg every 5 days, then stop; in patients taking 60 mg daily, reduce dose to 40 mg daily for 5 days, then 20 mg daily for 5 days, then 10 mg daily for 5 days, then stop.

Idiopathic thrombocytopenic purpura
Child: 1-10 yr: 1-2 mg/kg daily (max: 14 days) or 4 mg/kg daily (max: 4 days).

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

50ml/100ml bot Price : ৳60/95

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There are few similar medicines of Cortan are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.