Lebac Forte 250mg/5ml (Powder for Suspension)
Manufactured by: Square Cephalosporins Ltd.
Cephradine Similar medicine
Lebac Forte is indicated for
- Пневмония
- Фарингит
- Восприимчивые инфекции
- Средний отит
- Инфекции кожи и кожных структур
- Ревматическая лихорадка
- Тонзиллит
- Инфекции дыхательных путей
- Инфекции мочевыводящих путей
- Хирургическая профилактика
- Инфекции мочеполовых путей
- Острый простатит
Precautions and warnings
Особое внимание следует уделять пациентам с чувствительностью к пенициллину, почечной недостаточностью, беременным женщинам и матерям, кормящим своих детей грудным молоком.
Side-effects
- Диарея
- тошнота
- рвота; лейкопения
- нейтропения
- эозинофилия
- сыпь
- зуд; боль в суставах; увеличение АМК и креатина; головокружение. Потенциально смертельно: псевдомембранозный колит.
Drug Interactions
Петлевые диуретики повышают риск нефротоксичности. Почечный клиренс снижается при применении пробенецида.
При одновременном приеме нефротоксичных препаратов, таких как аминогликозиды, с цефрадином увеличивается риск повреждения почек. Почечная токсичность повышалась при применении диуретиков, таких как фуросемид, этакриновая кислота и пробенецид.
Contraindications
Порфирия и повышенная чувствительность к активному ингредиенту цефрадина или других цефалоспоринов.
Mode of actions
Цефрадин представляет собой цефалоспорин первого поколения, который блокирует последнюю стадию транспептидации продукции пептидогликана в клеточной стенке бактерий путем связывания с одним или несколькими пенициллин-связывающими белками (PBP), останавливая синтез клеточной стенки и вызывая гибель бактериальных клеток.
Dosage & Administration
Взрослые: ПО Восприимчивые инфекции 1-2 г/день в 2-4 приема. Макс: 4 г/день.
В/в/вм. Тяжелые инфекции 2–4 г/день в несколько приемов. Макс: 8 г/день.
Хирургическая профилактика 1-2 г перед операцией. Последующие дозы могут вводиться по мере необходимости.
Кожа, кожные структуры и инфекции дыхательных путей: обычная доза составляет 250 мг каждые 6 часов или 500 мг каждые 12 часов.
Крупозная пневмония: 500 мг каждые 6 часов или 1 г каждые 12 часов.
Инфекции мочевыводящих путей: обычная доза составляет 500 мг каждые 12 часов.
Инфекции желудочно-кишечного тракта: 500 мг три-четыре раза в день.
Дети: Перорально: обычная общая доза составляет 25–50 мг/кг/день, вводимая в 2–4 приема, разделенных поровну.
Инъекции: 50–100 мг/кг/день в 4 поровну разделенных дозы. Обычная общая доза может быть увеличена до 200-300 мг/кг/сут.
Периоперационная профилактика: рекомендуемая доза составляет 1–2 г внутримышечно или внутривенно; последующие парентеральные или пероральные дозы назначаются по мере необходимости.
Почечная недостаточность: пациентам, проходящим хронический прерывистый гемодиализ: можно ввести 250 мг в начале сеанса, повторить через 6–12 часов, затем снова через 36–48 часов после первой дозы и снова в начале следующего гемодиализа, если с момента приема предыдущей дозы прошло >30 часов.
CrCl (мл/мин)
>20 500 мг каждые 6 часов.
5–20 250 мг каждые 6 часов.
Pregnancy & Lactation
Хотя исследования на репродукции животных показали неблагоприятное воздействие, иногда даже неспособное продемонстрировать риск для плода, а адекватных и хорошо контролируемых исследований у беременных женщин нет, во время беременности это лекарство можно применять только тогда, когда это определенно необходимо.
Обсудите это со своими врачами и расскажите им отзывы об этом лекарстве.
Нет конкретной информации о том, передается ли это лекарство ребенку через грудное молоко. Перед кормлением грудью обсудите это с врачом.
Pack Size & Price
100ml bot Price : ৳120.36
Similar medicine
Manufactured by: Sanofi Aventis (BD) Ltd.
Manufactured by: Albion Laboratories Ltd.
Manufactured by: Healthcare Pharmaceuticals Ltd.
Manufactured by: Square Cephalosporins Ltd.
Manufactured by: Alco Pharma Limited
Manufactured by: Square Cephalosporins Ltd.
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