Erdon PLUS (Injection)
Manufactured by: Aristopharma Limited
Diclofenac + Lidocaine Hydrochloride Similar medicine
Erdon PLUS is indicated for
- Artrite reumatóide
- Osteoartrite
- Espondilite anquilosante
- Dor
- Gota aguda
- Inflamação
- Tendinite
- Queratoses actínicas
- Bursite
Precautions and warnings
Pessoas com histórico de úlceras estomacais, vômito com sangue, fezes pretas, colite ulcerativa, asma ou asma anterior, doença de Crohn, problemas de sangramento ou distúrbios sanguíneos precisam ter cuidado. Aqueles que têm problemas graves de fígado, coração ou rins, são idosos ou têm pressão alta atual ou passada devem ser monitorados de perto. Qualquer pessoa que tome AINEs (como Diclofenaco de sódio) por um longo período deve fazer check-ups regulares, incluindo exames de função renal, hepática e sanguínea. Se os testes hepáticos permanecerem anormais, piorarem ou aparecerem sintomas de doença hepática, o Diclofenaco sódico deve ser interrompido.
Side-effects
- Os efeitos colaterais do Diclofenaco são geralmente leves e transitórios. Geralmente é bem tolerado. No entanto
- no início do tratamento
- os pacientes podem por vezes queixar-se de desconforto gastrointestinal
- dor epigástrica
- eructação
- náuseas e diarreia
- podendo ocorrer
- por vezes
- dores de cabeça e hemorragias. Ocasionalmente
- foram relatadas erupções cutâneas
- edema periférico e anormalidades nas transaminases séricas. Os efeitos colaterais relatados muito raramente incluem ativação de úlcera péptica
- hematêmese ou melena
- discrasia sanguínea (uso extensivo). Houve relatos isolados de reações anafilactóides. Os efeitos adversos devidos à lidocaína envolvem principalmente o SNC
- são geralmente de curta duração e estão relacionados com a dose. A reação do SNC pode se manifestar por sonolência
- tontura
- desorientação
- confusão
- vertigens
- etc. No caso de colírios
- sensação de queimação ocular ou reação alérgica pode ocorrer em 5-10% dos pacientes.
Drug Interactions
O diclofenaco pode aumentar os níveis sanguíneos de metotrexato. Tomá-lo junto com outros AINEs ou anticoagulantes (como a varfarina) aumenta o risco de sangramento estomacal e intestinal. O risco de problemas renais é maior se usado com ciclosporina ou triantereno. Em pacientes com inflamação grave da córnea, o uso de colírio de diclofenaco com colírios de esteróides pode aumentar a chance de danos à córnea. A colestiramina e o colestipol diminuem a quantidade de diclofenaco que seu corpo absorve. Tomar diclofenaco após sucralfato diminui seu nível no sangue. Os colírios de diclofenaco podem tornar os colírios de acetilcolina e carbacol menos eficazes. O diclofenaco também pode aumentar os níveis sanguíneos de lítio e digoxina.
Os níveis sanguíneos de diclofenaco podem aumentar se tomado com cimetidina ou propranolol. Há uma chance maior de problemas cardíacos se tomado com betabloqueadores ou outros medicamentos para batimentos cardíacos irregulares. O diclofenaco administrado com fenitoína intravenosa pode aumentar os efeitos cardíacos indesejados. O baixo teor de potássio de medicamentos como acetazolamida, diuréticos de alça ou tiazidas pode reduzir o funcionamento da lidocaína. Se você usa fenitoína ou outros medicamentos indutores de enzimas por um longo período, pode precisar de doses mais altas.
Contraindications
Este medicamento não deve ser usado em pacientes com úlcera péptica ativa ou suspeita, sangramento gastrointestinal ou histórico de asma, urticária ou alergias nasais graves desencadeadas por aspirina ou outros AINEs.
A lidocaína não deve ser administrada a pacientes que sejam alérgicos a anestésicos locais do tipo amida.
Mode of actions
O diclofenaco é um AINE (antiinflamatório não esteróide) comum que pertence ao grupo do ácido fenilacético. Ajuda a reduzir a inflamação, a dor e a febre. Atua bloqueando a enzima ciclooxigenase, que diminui a produção de substâncias (prostaglandinas) que causam inflamação.
A lidocaína é um anestésico local do tipo amida. Ele atua estabilizando as membranas das células nervosas e bloqueando os íons de sódio, que são necessários para a transmissão dos sinais nervosos. No coração, a lidocaína diminui a atividade elétrica anormal e os sinais automáticos nos ventrículos e no sistema de condução (sistema His-Purkinje) e encurta o tempo de ativação das células cardíacas.
Dosage & Administration
Adultos: A dosagem é geralmente uma ampola de 75 mg por dia. Em casos graves (por exemplo, cólicas) a dose diária pode excepcionalmente ser aumentada para duas ampolas de 75 mg, separadas por um intervalo de algumas horas.
Crianças: Na artrite crônica juvenil, 1-3 mg de Diclofenaco sódico/kg de peso corporal diariamente em doses divididas.
Pacientes idosos: Recomenda-se a dosagem eficaz mais baixa, proporcional à idade e estado físico ou conforme prescrição médica.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
10 amps pack Price : ৳150
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