Fixal Plus 60 (Tablet)
Manufactured by: Opsonin Pharma Limited
Fexofenadine Hydrochloride + Pseudoephedrine Hydrochloride Similar medicine
Fixal Plus 60 is indicated for
- Allergic rhinitis
- Hay fever
- Urticaria
- Sneezing
- Runny nose
- Hives
- Skin rash
- Common cold
- Allergy
- Itchy or watery eyes
- Nasal congestion
Precautions and warnings
Do not use if you have an overactive thyroid (hyperthyroidism), heart problems such as heart disease, irregular heartbeat, or a fast heartbeat. Avoid if you have blood vessel diseases like hardening of the arteries (arteriosclerosis), high blood pressure, or aneurysms. It should also be avoided in people with diabetes, closed-angle glaucoma, kidney problems, or an enlarged prostate. Do not use during pregnancy or breastfeeding.
Side-effects
- Anginal pain; rebound congestion
- rhinorrhoea; fear
- anxiety
- restlessness
- tremor
- insomnia
- confusion
- irritability
- psychotic states; reduced appetite
- nausea
- vomiting; gangrene; cerebral haemorrhage
- pulmonary oedema; reflex bradycardia
- tachycardia
- cardiac arrhythmias
- palpitations
- cardiac arrest
- hypotension
- dizziness
- fainting
- flushing. Tissue necrosis
- sloughing; myocardial
- arterial necrosis.
Drug Interactions
There is a higher risk of high blood pressure and abnormal heart rhythms when this drug is used together with cardiac glycosides, quinidine, or tricyclic antidepressants (TCAs). The risk of blood vessel constriction goes up if it is given with ergot alkaloids or oxytocin. Taking it with MAO inhibitors (MAOIs) can cause a dangerous increase in blood pressure (hypertensive crisis). It may also interact with anesthetics like cyclopropane, halothane, and other halogenated anesthetics, as well as with medicines that lower blood pressure.
Contraindications
Severe hypertension, phaeochromocytoma.
Mode of actions
Fexofenadine is a medicine that comes from another drug called terfenadine. It works by blocking histamine H1 receptors outside the brain, which helps reduce allergy symptoms in the digestive system, blood vessels, and airways.
Pseudoephedrine works by activating both alpha (?) and beta (?) adrenergic receptors. When it stimulates ?-adrenergic receptors in the lining of the nose and airways, it causes blood vessels to tighten, which reduces swelling and stuffiness. When it activates ?-adrenergic receptors, it relaxes the muscles in the airways, helping you breathe easier, and also increases your heart rate and how strongly your heart beats.
Dosage & Administration
Adults and children 12 years of age and older: 1 tablet twice daily administered on an empty stomach with water.
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳165
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