Benadip 5/20 (Capsule)
Manufactured by: Incepta Pharmaceuticals Ltd.
Amlodipine + Benazepril Hydrochloride Similar medicine
Benadip 5/20 is indicated for
- 高血壓
Precautions and warnings
如果檢測到懷孕，請盡快停止使用氨氯地平+貝那普利。 建議老年人、腎或肝功能不全者、充血性心臟衰竭者、嚴重主動脈瓣狹窄者、單側或雙側腎動脈狹窄者、接受手術或麻醉者慎用。 氨氯地平和貝那普利的組合可能會引起症狀性低血壓，尤其是在鹽/容量不足的個體。 血管張力素轉換酶抑制劑 (ACEi) 與膽汁淤積性黃疸和爆發性肝壞死有關；如果患者出現黃疸或肝酵素大幅升高，請停止用藥。 應定期檢查腎功能和血液中的鉀含量。 在接受 ACEi 治療的個體中，已有臉部、四肢、嘴唇、舌頭、聲門、喉部和腸道血管性水腫的描述。 與所有 ACE 抑制劑一樣，它會導致慢性乾咳。 該藥物對兒童的安全性和有效性尚未確定。
Side-effects
- 咳嗽、水腫（包括依賴性水腫、血管性水腫、臉部水腫、週邊水腫）、頭痛、頭暈、臉潮紅、口乾、噁心、腹瀉、便秘、疲倦、疲勞、高鉀血症、低血壓、姿勢性低血壓、肌肉骨骼疼痛、皮疹、失眠、焦慮、性慾減退、急性腎病、心搏過、胸痛、心搏過酸升高、溶血性貧血、嗜中性白血球減少、血小板減少、胰臟炎、天皰瘡。 可能致命：過敏樣反應、血管性水腫、史蒂文斯-約翰遜症候群。
Drug Interactions
與消耗兒茶酚胺的藥物一起使用時，存在低血壓和/或明顯心搏過緩的風險。 為避免高血壓反跳，可樂定應在停用β受體阻斷劑幾天後停用；如果用β受體阻斷劑取代可樂定，則應在停用可樂定幾天后才開始使用β受體阻斷劑。 與前列腺素合成酶抑制劑（如吲哚美辛）同時使用可能會減弱β受體阻斷劑的降血壓作用。
Contraindications
有血管性水腫病史的患者以及孕婦和哺乳期婦女。
Mode of actions
氨氯地平是一種鈣拮抗劑，是一種二氫吡啶。 透過抑制跨膜鈣離子流入血管平滑肌和心肌，舒張冠狀血管平滑肌，引起冠狀血管舒張，進而降低血壓。 它也是周邊動脈的血管擴張劑。 貝那普利及其活性代謝物貝那普利拉可阻斷 ACE，導致血漿血管張力素 II 水準降低，進而降低醛固酮分泌。
Dosage & Administration
成人：口服 每粒複方膠囊含氨氯地平 2.5-10 mg 和貝那普利 10-40 mg：氨氯地平成分：2.5-10 mg，每日一次；貝那普利成分：10-40 mg，每日一次。
Pregnancy & Lactation
儘管動物生殖研究顯示對胎兒有不良影響，並且在孕婦中沒有充分且良好對照的研究，但在懷孕期間，儘管存在潛在風險，但在確實需要時可以使用該藥物。
另一項研究表明，懷孕期間不允許使用這種藥物。 如果您懷孕了，請勿使用它。 它可以透過皮膚和肺部吸收，從而損害未出生孩子的器官並導致先天性殘疾。 治療期間及停藥後六個月內嚴格有效的節育。 如果您確實懷孕了，請停止服用此藥並立即與您的醫生討論。
沒有關於這種藥物是否會進入母乳的具體資訊。 考慮到兒童可能存在的風險，不建議在使用該藥物時進行母乳喂養，並且至少在最後一次用藥後兩週進行母乳喂養。 哺乳前請先諮詢您的醫生。
Pack Size & Price
20's pack Price : ৳160
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