Avodil VL 5 (Tablet)
Manufactured by: Opsonin Pharma Limited
Amlodipine + Valsartan Similar medicine
Avodil VL 5 is indicated for
- Hipertensão
Precautions and warnings
ICC, síndrome do seio nasal, disfunção ventricular grave, cardiomiopatia hipertrófica e estenose aórtica grave são sintomas de insuficiência hepática ou renal. Em pacientes com estenose subaórtica hipertrófica idiopática, usar com cautela. Crianças, idosos. Lactação e gravidez.
Side-effects
- Dor de cabeça
- edema periférico
- fadiga
- sonolência
- náusea
- dor abdominal
- rubor
- dispepsia
- palpitações
- tonturas. Raramente prurido
- erupção cutânea
- dispneia
- astenia
- cãibras musculares. Potencialmente Fatal: Hipotensão
- bradicardia
- atraso do sistema condutivo e FCC.
Drug Interactions
Amlodipina: Quando usado com inibidores do CYP3A4, as concentrações plasmáticas podem aumentar (por exemplo, antifúngicos azólicos, ritonavir). A sinvastatina e medicação concomitante podem aumentar o risco de miopatia, incluindo rabdomiólise. Os níveis plasmáticos de conivaptano e ciclosporina podem estar aumentados.
Valsartana: Quando usado com AINEs, tem potencial para neutralizar os efeitos hipotensores e aumentar o risco de insuficiência renal. Com diuréticos poupadores de K, suplementos de K ou substitutos de sal contendo K, há um risco maior de hipercalemia.
Quando administrado juntamente com aliscireno em indivíduos com diabetes e insuficiência renal, existe um risco aumentado de hipotensão, hipercalemia e anomalias na função renal (incluindo insuficiência renal aguda).
Contraindications
A hipersensibilidade às dihidropiridinas é conhecida.
Mode of actions
A amlodipina relaxa o músculo liso das artérias periféricas e coronárias. Durante a despolarização, inibe a entrada de íons Ca nos canais lentos ou seleciona canais sensíveis à voltagem do músculo liso vascular e do coração, resultando em vasodilatação coronariana. Em pacientes com angina vasospástica, também melhora o fornecimento de oxigênio ao miocárdio.
Valsartan é um antagonista do receptor da angiotensina II tipo 1 (AT1) que reduz a pressão arterial ao bloquear a vasoconstrição induzida pela angiotensina II, a produção de aldosterona e a reabsorção de sódio no rim.
Dosage & Administration
Adulto: PO Iniciar com 5 mg/160 mg uma vez ao dia.
Pode aumentar a dose após pelo menos 2 semanas, não excedendo 10 mg/dia de amlodipina e 320 mg/dia de valsartana uma vez ao dia, se necessário.
Pregnancy & Lactation
Embora estudos de reprodução animal tenham demonstrado um efeito adverso no feto e não existam estudos adequados e bem controlados em mulheres grávidas, mas durante a gravidez, este medicamento pode ser utilizado apenas quando definitivamente necessário, apesar dos riscos potenciais.
Outro estudo mostra que este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
30's pack Price : ৳270
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There are few similar medicines of Avodil VL 5 are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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