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Gpentin 600mg (Tablet)

Manufactured by: Opsonin Pharma Limited

Gabapentin Similar medicine

Gpentin is indicated for

  • Epilepsy
  • Neuropathic pain
  • Partial Seizures
  • Hot flashes
  • Fibromyalgia
  • Postherpetic Neuralgia
  • Pain from diabetic neuropathy.

Precautions and warnings

Stop or switch from other epilepsy medicines with caution, especially if you have a history of mental health issues, kidney problems, or are pregnant. Reduce the dose gradually over at least 7 days to avoid more frequent seizures.

Side-effects

  • Somnolence
  • dizziness
  • ataxia
  • weakness
  • paraesthesia
  • fatigue
  • headache; nystagmus
  • diplopia; nausea
  • vomiting
  • wt gain
  • dyspepsia; rhinitis; tremor; leucopenia; altered LFTs; Stevens-Johnson syndrome.

Drug Interactions

Taking this with morphine may raise its level in your blood. If you take it with antacids, your body may not absorb it as well.

Contraindications

Hypersensitivity. Lactation.

Mode of actions

Gabapentin is similar in structure to the brain chemical GABA, but it does not act like GABA or block its effects. Gabapentin mainly binds to certain sites in the brain, which are linked to voltage-gated calcium channels, especially those with the ?-2/?-1 subunit. These channels are mostly found at the ends of nerve cells (presynaptic) and help regulate the release of stimulating neurotransmitters. This process is important because it can affect conditions like epilepsy and the sensation of pain.

Dosage & Administration

Adult: PO: Neuropathic pain: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 1800 mg daily in three divided doses.

Partial seizure/epilepsy: 300 mg on day-1, then 300 mg twice on day-2, then 300 mg thrice on day-3, then increase the dose according to response in steps of 300 mg daily to maximum 2400 mg daily in three divided doses.

In case of children: For 6-12 years - 10 mg/kg on day-1, then 20 mg/kg on day-2, then 25-35 mg/kg daily in 3 divided doses. Maintenance dose is 900 mg daily (body weight 26-36 Kg) or 1.2 gm daily (body weight 37-50 Kg).

Renal impairment: Haemodialysis: Loading dose: 300-400 mg followed by 200-300 mg after each 4 hr of haemodialysis.
CrCl (ml/min)

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price

20's pack Price : ৳600

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Click here to see 20 more similar medicines

There are few similar medicines of Gpentin are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.