Genacyn (Ointment)
Manufactured by: Square Pharmaceuticals Ltd.
Gentamicin 0.1% Topical Similar medicine
Genacyn is indicated for
- الالتهابات الجلدية البكتيرية، الحروق، الأكزيما، التهاب الجلد الدهني، الإكزيما، التسحج، التهاب الجريبات، الدمامل، لدغات ولسعات الحشرات، التمزقات والسحجات، الداحس، تقيح الجلد الغنغريني، الخراجات والخراجات الجلدية، قرح الركود وتقرحات الجلد المصابة، العدوى البكتيرية أو الفطرية أو الفيروسية، الفطار الذبابي، البسيط الجروح الجراحية، التهاب الجلد التماسي المصاب الناجم عن الكائنات الحساسة.
Precautions and warnings
كن حذرًا عند استخدام عوامل الحصر العصبي العضلي في نفس الوقت، أو عند الأشخاص الذين يعانون من الوهن العضلي الوبيل، أو مرض باركنسون، أو الحالات التي تزيد من خطر تلف الأذن أو الكلى. توخي الحذر أثناء الرضاعة الطبيعية. فحص مستويات الجنتاميسين في الدم لدى المرضى الذين يتلقون جرعات عالية أو علاج طويل الأمد، وكذلك عند الرضع، والمرضى المسنين، والذين يعانون من مشاكل في الكلى، والتليف الكيسي، أو السمنة المفرطة. مراقبة السمع ووظائف الكلى بانتظام.
Side-effects
- الدوخة أو الدوار. الفشل الكلوي الحاد، التهاب الكلية الخلالي، نخر أنبوبي حاد؛ اختلال توازن المنحل بالكهرباء. ارتفاع عابر في البيليروبين في الدم ونواقل الأمين. فرفرية. الغثيان والقيء. التشنجات والاكتئاب العقلي والهلوسة. ضمور أو نخر الفئران في مواقع الحقن. قد تكون مميتة: السمية الكلوية، السمية الأذنية والحصار العصبي العضلي (قد يكشف الوهن العضلي الوبيل أو يؤدي إلى تفاقمه).
Drug Interactions
يعمل هذا الدواء بشكل جيد مع الأمبيسيلين والبنزيل بنسلين والمضادات الحيوية الأخرى من نوع بيتا لاكتام. هناك خطر أكبر للإصابة بمشاكل خطيرة في التنفس إذا تم استخدامه مع أدوية التخدير أو مسكنات الألم الأفيونية. يمكن أن يقلل أيضًا من إزالة زالسيتابين عن طريق الكلى وقد يسبب انخفاض مستويات الكالسيوم إذا تم تناوله مع البايفوسفونيت. لا تستخدمه مع agalsidase alfa أو beta، لأنه يمكن أن يمنع عمل ?-galactosidase.
**الآثار القاتلة المحتملة:**
- يزداد خطر تلف الأذن (التسمم الأذني) إذا تم استخدامه مع حمض الإيثاكرينيك أو فوروسيميد.
- يزداد خطر تلف الكلى (السمية الكلوية) عند دمجه مع السيفالوسبورينات، السيكلوسبورين، السيسبلاتين، الفانكومايسين، الهيدروكورتيزون، أو الإندوميتاسين.
- يمكن أن يعزز تأثيرات الأدوية التي تمنع الإشارات العصبية العضلية (عوامل الحصر العصبي العضلي).
Contraindications
لا تستخدمه إذا كان لديك رد فعل تحسسي تجاه الأمينوغليكوزيدات، أو كنت حاملاً، أو كنت تعاني من مشاكل في الكبد، أو لديك ثقب في طبلة الأذن.
Mode of actions
الجنتاميسين هو نوع من المضادات الحيوية يسمى أمينوغليكوزيد. وهو يعمل عن طريق الارتباط بأجزاء الثلاثينيات والخمسينيات من ريبوسومات البكتيريا المسؤولة عن صنع البروتينات. وهذا يمنع البكتيريا من صنع البروتينات التي تحتاجها ويدمر غشاء الخلية، مما يسهل قتلها.
Dosage & Administration
للبالغين: كريم 0.1%؛ تنطبق على المنطقة المصابة 3-4 مرات يوميا.
Pregnancy & Lactation
على الرغم من أن دراسات التكاثر الحيواني أظهرت تأثيرًا سلبيًا على الجنين ولا توجد دراسات كافية ومراقبة بشكل جيد عند النساء الحوامل، إلا أنه خلال فترة الحمل، يمكن استخدام هذا الدواء فقط عندما تكون هناك حاجة إليه بالتأكيد على الرغم من المخاطر المحتملة.
نادراً ما تظهر على الأمهات اللاتي لديهن طفل حديث الولادة والذين استخدموا هذا الدواء خلال الأشهر الثلاثة الأخيرة من الحمل أعراض بما في ذلك النعاس، وتصلب العضلات أو الارتعاش، ومشاكل التغذية أو التنفس، والبكاء المستمر. إذا لاحظت أياً من هذه الأعراض لدى طفلك خاصة خلال شهره الأول، أخبري الطبيب فوراً.
ينتقل هذا الدواء إلى حليب الثدي. تحدثي مع طبيبك قبل الرضاعة الطبيعية.
Pack Size & Price
10gm tube Price : ৳12.05
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Manufactured by: Square Pharmaceuticals Ltd.
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List of medicines using Gentamicin 0.1% TopicalGentamicin 0.3% Topical is indicated for Bacterial skin infections, Burns, eczema, seborrheic dermatitis, ecthyma, excoriation, folliculitis, furunculosis, insect bites and stings, lacerations and abrasions, paronychia, pyoderma gangrenosum, skin cysts and abscesses, stasis ulcers and infected skin ulcers, bacterial, fungal or viral superinfection, sycosis barbae, minor surgical wounds, infected contact dermatitis caused by susceptible organisms.
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List of medicines using Gentamicin 0.1% TopicalGentamicin 0.3% Topical is indicated for Bacterial skin infections, Burns, eczema, seborrheic dermatitis, ecthyma, excoriation, folliculitis, furunculosis, insect bites and stings, lacerations and abrasions, paronychia, pyoderma gangrenosum, skin cysts and abscesses, stasis ulcers and infected skin ulcers, bacterial, fungal or viral superinfection, sycosis barbae, minor surgical wounds, infected contact dermatitis caused by susceptible organisms.
List of medicines using Gentamicin 0.3% Topical
