Inopil PLUS 2/625 (Tablet)
Manufactured by: Delta Pharma Limited
Indapamide + Perindopril Erbumine Similar medicine
Inopil PLUS 2/625 is indicated for
- Hipertensi
Precautions and warnings
Orang yang memakai obat ini mungkin memiliki masalah dengan ginjal, tekanan darah rendah, atau ketidakseimbangan elektrolit. Penting untuk memeriksa secara teratur seberapa baik ginjal Anda bekerja dan memantau kadar kalium dalam darah Anda. Jika Anda menderita diabetes, kadar gula darah Anda juga harus diperiksa, terutama jika potasium Anda rendah. Ada kemungkinan lebih tinggi terkena jumlah sel darah putih yang rendah (neutropenia atau agranulositosis) jika sistem kekebalan tubuh Anda lemah. Jika Anda mengalami pembengkakan pada wajah, tangan, bibir, lidah, tenggorokan, atau kotak suara (tanda-tanda angioedema), segera hentikan penggunaan obat dan dapatkan bantuan medis.
Side-effects
- Batuk kering
- sakit kepala
- bradikardia
- pusing
- astenia
- hipokalemia
- dan hipotensi ortostatik. Efek GI seperti konstipasi
- mulut kering
- mual
- nyeri epigastrium
- anoreksia
- nyeri perut dan gangguan pengecapan.
Drug Interactions
Menggunakan obat ini dengan obat tekanan darah lain atau diuretik dapat meningkatkan efeknya. Ada risiko lebih tinggi mengalami kalium rendah (hipokalemia) jika dikonsumsi dengan kortikosteroid, kortikotropin, atau amfoterisin.
**Peringatan:** Hal ini dapat meningkatkan risiko keracunan litium yang serius. Kalium yang rendah juga dapat membuat efek samping dari digitalis (obat jantung) menjadi lebih berbahaya.
Contraindications
Hipersensitivitas. Gangguan ginjal berat CrCl
Mode of actions
Perindopril adalah sejenis obat yang disebut ACE inhibitor. Ia bekerja dengan menghentikan tubuh mengubah angiotensin I menjadi angiotensin II, yang membantu menurunkan tekanan darah dengan merelaksasi pembuluh darah dan mengurangi beban kerja pada jantung. Ini juga memblokir enzim yang disebut kininase, yang mempengaruhi bahan kimia tubuh tertentu seperti bradikinin.
Indapamide adalah obat lain yang membantu menurunkan tekanan darah. Ini terkait dengan sulfonamid dan memiliki struktur kimia khusus yang disebut cincin indole. Indapamide bekerja dengan menghentikan ginjal menyerap kembali natrium di area tertentu, sehingga lebih banyak natrium dan air dikeluarkan melalui urin. Hal ini meningkatkan jumlah urin dan membantu mengurangi tekanan darah.
Dosage & Administration
Dewasa: PO Per tab mengandung perindopril 4 mg dan indapamide 1,25 mg: 1 tab sekali sehari.
Gangguan ginjal:
CrCl (ml/menit)
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
20's pack Price : ৳160
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Click here to see 7 more similar medicines
There are few similar medicines of Inopil PLUS 2/625 are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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