Neofenac (Gel)
Manufactured by: Ad-din Pharmaceuticals Ltd.
Diclofenac Sodium 1% Topical Similar medicine
Neofenac is indicated for
- Artritis reumatoid
- Osteoartritis
- Nyeri sendi dan otot
Precautions and warnings
Tukak lambung atau perdarahan gastrointestinal jarang terjadi pada orang yang menggunakan Diklofenak. Pasien yang lebih tua harus diawasi dengan cermat. Gel tidak boleh menyentuh mata, bagian dalam mulut, atau hidung Anda. Setelah memakai gel, cuci tangan Anda dengan baik dan jangan ditelan.
Side-effects
- Umumnya ditoleransi dengan baik. Efek samping bersifat ringan
- jarang dan bersifat sementara. Namun
- pada awal pengobatan
- pasien terkadang mengeluh nyeri epigastrium
- bersendawa
- mual dan diare
- pusing
- atau sakit kepala. Efek ini biasanya bersifat ringan. Edema perifer dan reaksi kulit
- seperti ruam dan eksim juga pernah ditemui. Gel dapat menyebabkan iritasi lokal dan kemerahan pada kulit serta ruam kulit.
Drug Interactions
- Diklofenak dapat meningkatkan kadar metotreksat dalam darah Anda.
- Mengonsumsi diklofenak dengan NSAID lain atau pengencer darah (seperti warfarin) meningkatkan risiko pendarahan lambung atau usus.
- Menggunakannya bersama dengan ciclosporin atau triamterene dapat meningkatkan risiko masalah ginjal.
- Jika Anda sudah mengalami peradangan kornea yang serius, penggunaan obat tetes mata diklofenak bersama dengan obat tetes mata steroid dapat meningkatkan kemungkinan masalah kornea.
- Colestyramine dan colestipol dapat menurunkan jumlah diklofenak yang diserap tubuh Anda.
- Mengonsumsi sukralfat sebelum diklofenak dapat menurunkan kadar diklofenak dalam darah.
- Obat tetes mata diklofenak dapat membuat obat mata asetilkolin dan karbachol menjadi kurang efektif.
- Diklofenak dapat meningkatkan kadar litium dan digoksin dalam darah Anda.
Contraindications
Produk ini tidak boleh digunakan oleh orang yang alergi terhadap bahan-bahannya. Obat ini juga tidak cocok untuk penderita tukak lambung atau alergi terhadap diklofenak, obat serupa, atau obat antiinflamasi nonsteroid (NSAID) lainnya. Diklofenak tidak boleh digunakan oleh pasien asma yang serangannya dipicu oleh aspirin atau obat lain yang menghambat produksi prostaglandin. Selain itu, jangan mengoleskan gel di bawah perban atau balutan kedap udara.
Mode of actions
Diklofenak adalah NSAID (obat antiinflamasi nonsteroid) umum yang termasuk dalam kelompok asam fenilasetat. Ini sangat mengurangi peradangan, mengurangi rasa sakit, dan menurunkan demam. Diklofenak bekerja dengan memblokir enzim COX-1 dan COX-2, yang dibutuhkan untuk membuat prostaglandin, zat penyebab peradangan dan nyeri. Hal ini juga dapat membantu dengan mengurangi aktivitas sel kekebalan tertentu (neutrofil dan limfosit), menurunkan bahan kimia terkait peradangan (sitokin), dan mengurangi pergerakan sel inflamasi ke lokasi cedera.
Dosage & Administration
Gel: Hanya untuk pemakaian luar. Tergantung pada ukuran area yang akan dirawat, 2-4 g Gel harus dioleskan ke kulit 3-4 kali sehari. Ke daerah yang terkena gel harus digosok ringan.
Gel juga dapat diberikan sebagai tambahan pengobatan lebih lanjut dengan bentuk sediaan Diklofenak lainnya.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
25 gm tube Price : ৳12.9
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