Nupralgin Plus 500 (Tablet)
Manufactured by: Ibn Sina Pharmaceutical Ind. Ltd.
Esomeprazole + Naproxen Similar medicine
Nupralgin Plus 500 is indicated for
- Artrite reumatóide
- Osteoartrite
- Espondilite anquilosante
- Rigidez articular
Precautions and warnings
Informe o seu médico se você já teve asma, doença hepática, sangramento, úlceras, azia recorrente, doença cardíaca, como histórico de ataque cardíaco, pressão alta, acidente vascular cerebral, edema, retenção de líquidos, níveis baixos de sódio no sangue, doenças sanguíneas como anemia, sangramento ou problemas de coagulação, pólipos nasais ou lúpus antes de tomar este medicamento.
Os medicamentos AINE, como o naproxeno, podem causar dificuldades renais em certas pessoas. Se você está desidratado, tem insuficiência cardíaca ou doença renal, é um adulto mais velho ou toma certos medicamentos, é mais provável que tenha problemas. Para evitar a desidratação, beba muitos líquidos conforme recomendado pelo seu médico e relate imediatamente quaisquer alterações na quantidade de urina ao seu médico.
Este medicamento pode causar tonturas ou sonolência. Você pode ficar tonto ou sonolento se consumir álcool ou cannabis. Não dirija, opere máquinas ou participe de qualquer outra atividade que exija atenção até ter certeza de que pode fazê-lo com segurança. Limite a ingestão de bebidas alcoólicas. Se você usa cannabis, converse com seu médico.
Este medicamento tem potencial para induzir sangramento estomacal. O uso regular de álcool e tabaco, especialmente em combinação com esta prescrição, pode aumentar o risco de sangramento estomacal. Para mais informações fale com o seu médico ou farmacêutico.
Side-effects
- Em geral
- As reações adversas mais comuns em ensaios clínicos (>5%): gastrite erosiva
- dispepsia
- gastrite
- diarreia
- úlcera gástrica
- dor abdominal superior
- náuseas
- etc.
Drug Interactions
Aliscireno, inibidores da ECA como captopril e lisinopril, bloqueadores dos receptores da angiotensina II como valsartana e losartana, corticosteróides como prednisona, lítio, metotrexato, especialmente terapia em altas doses, e rifampicina são alguns dos produtos que podem interagir com este medicamento.
Quando combinado com outros medicamentos que podem causar sangramento, este medicamento pode aumentar o risco de sangramento. Medicamentos antiplaquetários como o clopidogrel, bem como “anticoagulantes” como dabigatrana/enoxaparina/varfarina, são exemplos.
Alguns produtos requerem que o ácido estomacal seja adequadamente absorvido pelo organismo. Como o esomeprazol reduz a acidez estomacal, ele pode afetar a eficácia do desempenho desses medicamentos. Atazanavir, erlotinibe, nelfinavir, pazopanibe, rilpivirina e certos antifúngicos azólicos como itraconazol, cetoconazol e posaconazol estão entre os produtos afetados.
Contraindications
• Hipersensibilidade a qualquer um dos ingredientes do Progesic ou benzimidazóis substituídos.
• Asma, urticária ou outras reações alérgicas após o uso de aspirina ou outros antiinflamatórios não esteroides
• No caso de cirurgia de revascularização do miocárdio (CRM), utilizar durante o período perioperatório.
• Uma senhora que está no final da gravidez.
Mode of actions
Um AINE prototípico é o naproxeno, um derivado do ácido propiônico. Inibe as enzimas ciclooxigenase-1 e -2 (COX-1 e -2) de forma reversível, resultando na redução da síntese de precursores de prostaglandinas. Possui propriedades antiinflamatórias, analgésicas e antipiréticas, além de inibir a agregação plaquetária.
O esomeprazol é um inibidor da bomba de prótons (IBP) que inibe a H+/K+ ATPase na célula parietal gástrica, suprimindo a produção de ácido gástrico. É o isômero S do omeprazol.
Dosage & Administration
Artrite Reumatóide, Osteoartrite, Espondilite Alquilosante e dismenorreia: 375 ou 500 mg, um comprimido duas vezes ao dia.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
30's pack Price : ৳300
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