Oflacin 200mg (Tablet)
Manufactured by: Drug International Ltd.
Ofloxacin Similar medicine
Oflacin is indicated for
- Lepra
- bronquitis crónica; Neumonía adquirida en la comunidad; Infecciones cutáneas no complicadas
- ántrax
- enfermedad del legionario
- cervicitis no gonocócica; Uretritis
- cistitis no complicada
- ITU complicada
- diarrea del viajero
- próstata bacteriana
- fiebre tifoidea
- infecciones de la piel y los tejidos blandos
- gonorrea no complicada
- enfermedad inflamatoria pélvica
- infecciones del tracto respiratorio inferior
- septicemia.
Precautions and warnings
Las personas con epilepsia o tendencia a sufrir convulsiones, aquellas que tienen o sospechan problemas con su sistema nervioso central, problemas renales o hepáticos, miastenia gravis o que corren riesgo de desarrollar infecciones secundarias (sobreinfecciones), así como los niños, deben tener precaución.
Side-effects
- Náuseas
- vómitos
- dolor abdominal
- diarrea; dolor de cabeza
- mareos
- insomnio
- alucinaciones; leucopenia y eosinofilia; vaginitis; disgeusia; daño y rotura del tendón; anorexia; temblor; fotosensibilidad; reacciones de hipersensibilidad. Suspender si se producen reacciones psiquiátricas
- neurológicas o de hipersensibilidad. Potencialmente fatal: anafilaxia; raramente convulsiones.
Drug Interactions
Tomar ciertos medicamentos antiarrítmicos de clase IA (como quinidina, procainamida) o clase III (como amiodarona, sotalol) al mismo tiempo puede aumentar el riesgo de un ritmo cardíaco peligroso (prolongación del intervalo QT). Los antiácidos que contienen magnesio, aluminio o calcio pueden reducir la cantidad de medicamento en la sangre y la orina. Cuando se toman con antibióticos aminoglucósidos (como amikacina, tobramicina), puede haber un efecto antibacteriano más fuerte. El uso de corticosteroides al mismo tiempo puede aumentar el riesgo de sufrir problemas graves en los tendones. Los AINE pueden aumentar el riesgo de sufrir efectos secundarios en el sistema nervioso, como convulsiones. Tomar este medicamento con teofilina puede causar niveles de teofilina más altos y duraderos en la sangre, lo que aumenta el riesgo de efectos secundarios de la teofilina.
Contraindications
No lo use si es alérgico a las quinolonas, está embarazada o amamantando, tiene un intervalo QT prolongado o tiene niveles bajos de potasio no tratados (hipopotasemia).
Mode of actions
La ofloxacina es un tipo de antibiótico fluoroquinolona que actúa bloqueando las enzimas bacterianas llamadas topoisomerasa IV y ADN girasa, que son necesarias para que las bacterias copien, reparen y produzcan su ADN. Esto lo hace eficaz contra muchos tipos de bacterias gramnegativas y grampositivas.
Dosage & Administration
Adulto: VO Parte de la politerapia en lepra 400 mg/día o de forma intermitente, según pauta. Gonorrea no complicada Dosis única de 400 mg. Exacerbación bacteriana aguda de la bronquitis crónica;
Neumonía adquirida en la comunidad; Infecciones cutáneas no complicadas 400 mg dos veces al día durante 10 días. Enfermedad inflamatoria pélvica 400 mg dos veces al día durante 14 días. Profilaxis posexposición después de la exposición al ántrax por inhalación, 400 mg dos veces al día durante 60 días.
Enfermedad del legionario 400 mg dos veces al día durante 2-3 semanas. Infección mixta de uretra y cuello uterino por C. trachomatis y Neisseria gonorrhoeae; cervicitis no gonocócica; Uretritis por Chlamydia trachomatis 200-300 mg dos veces al día durante 7 días.
Cistitis no complicada 200 mg dos veces al día durante 3 a 7 días. La duración depende del agente causal. ITU complicada 200 mg dos veces al día durante 10 días. Diarrea del viajero 300 mg dos veces al día durante 1 a 3 días. Próstata bacteriana crónica 300 mg dos veces al día durante 6 semanas. Fiebre tifoidea 200-400 mg dos veces al día durante 7-14 días.
intravenoso
Adultos: 200 mg al día mediante infusión intravenosa durante al menos 30 minutos. Máx.: 400 mg dos veces al día infundidos durante al menos 1 hora.
Insuficiencia renal: dosis inicial normal y luego reducir.
ClCr (ml/min)
20-50 Reducir la dosis a la mitad o administrar la dosis habitual sólo cada 24 horas.
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso en el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario a pesar de los riesgos potenciales.
Las madres con un bebé recién nacido que han usado este medicamento durante los últimos 3 meses del embarazo rara vez presentan síntomas que incluyen somnolencia, rigidez o temblores musculares, problemas para alimentarse o respirar, y llanto constante. Si nota alguno de estos síntomas en su bebé, especialmente durante el primer mes, informe al médico de inmediato.
Este medicamento pasa a la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
20's pack Price : ৳240
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Manufactured by: Drug International Ltd.
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