Oflacin 200mg (Tablet)
Manufactured by: Drug International Ltd.
Ofloxacin Similar medicine
Oflacin is indicated for
- Lèpre
- bronchite chronique ; Pneumonie communautaire ; Infections cutanées simples
- charbon
- maladie du légionnaire
- cervicite non gonococcique ; Urétrite
- cystite non compliquée
- infection urinaire compliquée
- diarrhée du voyageur
- prostatite bactérienne
- fièvre typhoïde
- infections de la peau et des tissus mous
- gonorrhée non compliquée
- maladie inflammatoire pelvienne
- infections des voies respiratoires inférieures
- septicémie
Precautions and warnings
Les personnes épileptiques ou ayant tendance à avoir des convulsions, celles qui ont connu ou soupçonné des problèmes avec leur système nerveux central, des problèmes rénaux ou hépatiques, une myasthénie grave ou qui risquent de développer des infections secondaires (surinfections), ainsi que les enfants, doivent faire preuve de prudence.
Side-effects
- Nausées
- vomissements
- douleurs abdominales
- diarrhée ; maux de tête
- vertiges
- insomnie
- hallucinations ; leucopénie et éosinophilie ; vaginite; dysgueusie; lésions et ruptures de tendons ; anorexie; tremblement; photosensibilité; réactions d'hypersensibilité. Arrêtez si des réactions psychiatriques
- neurologiques ou d'hypersensibilité surviennent. Potentiellement mortel : Anaphylaxie ; rarement des convulsions.
Drug Interactions
La prise simultanée de certains médicaments antiarythmiques de classe IA (comme la quinidine, la procaïnamide) ou de classe III (comme l'amiodarone, le sotalol) peut augmenter le risque d'un rythme cardiaque dangereux (allongement de l'intervalle QT). Les antiacides contenant du magnésium, de l'aluminium ou du calcium peuvent réduire la quantité de médicament dans votre sang et votre urine. Lorsqu'il est pris avec des antibiotiques aminosides (comme l'amikacine, la tobramycine), il peut y avoir un effet antibactérien plus fort. L’utilisation concomitante de corticostéroïdes peut augmenter le risque de problèmes tendineux graves. Les AINS peuvent augmenter le risque d’effets secondaires sur le système nerveux, tels que des convulsions. Prendre ce médicament avec de la théophylline peut entraîner des taux de théophylline plus élevés et plus durables dans votre sang, augmentant ainsi le risque d'effets secondaires liés à la théophylline.
Contraindications
Ne pas utiliser si vous êtes allergique aux quinolones, si vous êtes enceinte ou si vous allaitez, si vous avez un intervalle QT prolongé ou si vous avez de faibles taux de potassium non traités (hypokaliémie).
Mode of actions
L'ofloxacine est un type d'antibiotique fluoroquinolone qui agit en bloquant les enzymes bactériennes appelées topoisomérase IV et ADN gyrase, qui sont nécessaires aux bactéries pour copier, réparer et produire leur ADN. Cela le rend efficace contre de nombreux types de bactéries à Gram négatif et à Gram positif.
Dosage & Administration
Adulte : PO Dans le cadre d'une polychimiothérapie dans la lèpre 400 mg/jour ou par intermittence selon le schéma thérapeutique. Gonorrhée sans complication Dose unique de 400 mg. Exacerbation bactérienne aiguë de bronchite chronique ;
Pneumonie communautaire ; Infections cutanées non compliquées 400 mg deux fois par jour pendant 10 jours. Maladie inflammatoire pelvienne 400 mg deux fois par jour pendant 14 jours. Prophylaxie post-exposition après exposition à l'anthrax par inhalation 400 mg deux fois par jour pendant 60 jours.
Maladie du légionnaire 400 mg deux fois par jour pendant 2-3 semaines. Infection mixte de l'urètre et du col de l'utérus due à C. trachomatis et Neisseria gonorrhoeae ; Cervicite non gonococcique ; Urétrite due à Chlamydia trachomatis 200 à 300 mg deux fois par jour pendant 7 jours.
Cystite non compliquée 200 mg deux fois par jour pendant 3 à 7 jours. La durée dépend de l'agent causal. UTI compliquée 200 mg deux fois par jour pendant 10 jours. Diarrhée du voyageur 300 mg deux fois par jour pendant 1 à 3 jours. Prostatite bactérienne chronique 300 mg deux fois par jour pendant 6 semaines. Fièvre typhoïde 200 à 400 mg deux fois par jour pendant 7 à 14 jours.
Intraveineuse
Adulte : 200 mg par jour en perfusion IV pendant au moins 30 min. Max : 400 mg bid en perfusion pendant au moins 1 heure.
Insuffisance rénale : dose initiale normale, puis réduite.
ClCr (ml/min)
20-50 Réduire la dose de moitié ou administrer la dose habituelle uniquement toutes les 24 heures.
Pregnancy & Lactation
Bien que des études sur la reproduction animale aient montré un effet indésirable sur le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste lorsque cela est absolument nécessaire, malgré les risques potentiels.
Les mères d'un nouveau-né qui ont utilisé ce médicament au cours des 3 derniers mois de leur grossesse peuvent rarement créer des symptômes tels que somnolence, raideur ou tremblements musculaires, troubles de l'alimentation ou de la respiration, pleurs constants. Si vous remarquez l'un de ces symptômes chez votre bébé, en particulier au cours de son premier mois, informez-en immédiatement le médecin.
Ce médicament passe dans le lait maternel. Parlez-en à votre médecin avant d'allaiter.
Pack Size & Price
20's pack Price : ৳240
Similar medicine
Manufactured by: Square Pharmaceuticals Ltd.
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Manufactured by: Drug International Ltd.
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