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Atechlor 100 (Tablet)

Manufactured by: Silva Pharmaceuticals Ltd.

Atenolol + Chlorthalidone Similar medicine

Atechlor 100 is indicated for

  • Hypertension

Precautions and warnings

Bronchospastic illness in the elderly, renal or hepatic impairment It's possible that it'll make your peripheral arterial circulation problem worse. Beta-blockers can reduce myocardial contractility, and long-term usage in patients without a history of cardiac failure can lead to cardiac failure in some situations. Patients receiving anesthetic drugs should be cautious since they may depress the myocardium. Acute withdrawal in patients with coronary artery disease can worsen angina pectoris and lead to a heart attack. Hypoglycemia and thyrotoxicosis symptoms (tachycardia) may be masked with atenolol. Chlorthalidone therapy may cause latent DM to appear. Hyperuricaemia and gout can both be caused by chlorthalidone. Renal function, potassium levels, and symptoms of fluid and electrolyte imbalance should all be monitored. If you notice signs of growing renal impairment, stop taking it. Pregnancy and lactation are not advised. The drug's safety and efficacy in children have yet to be determined.

Side-effects

  • Atenolol: Dyspnoea
  • wheeziness
  • bradycardia
  • hypotension
  • cold extremities
  • fatigue
  • dizziness
  • insomnia
  • lethargy
  • confusion
  • headache
  • depression
  • nightmares
  • nausea
  • diarrhoea
  • constipation
  • impotence
  • paraesthesia
  • rash
  • Raynaud's phenomenon. Chlorthalidone: Orthostatic hypotension
  • GI disturbances
  • jaundice
  • pancreatitis
  • vertigo
  • lethargy
  • paraesthesia
  • photosensitivity
  • rash
  • muscle cramps
  • hypokalaemia
  • hyponatraemia
  • hyperglycaemia
  • hyperuricaemia or gout
  • leucopenia
  • agranulocytosis
  • aplastic anaemia
  • thrombocytopenia. Potentially Fatal: Atenolol: Heart failure
  • 2nd or 3rd degree AV block. Chlorthalidone: Hypersensitivity reaction including toxic epidermal necrolysis.

Drug Interactions

Concurrent administration of reserpine and other drugs might cause hypotension and bradycardia. Channel blockers, hydralazine, and methyldopa are all additives. Verapamil and diltiazem increase the risk of bradycardia and heart block. Along with NSAIDs, it may help to reduce hypotensive symptoms (for example, indomethacin). Disopyramide, amiodarone, or digitalis glycosides have a stronger bradycardic impact. When clonidine is stopped, it might cause rebound hypertension.

Contraindications

Hypersensitivity to either product or sulphonamide derivatives, sinus bradycardia, 2nd or 3rd-degree heart block, cardiogenic shock, and anuria.

Mode of actions

Atenolol is an adrenergic receptor blocker that acts primarily on the heart's first adrenergic receptors. Chlorthalidone is a thiazide-like diuretic that lowers blood pressure by blocking sodium reabsorption at the distal convoluted tubule's commencement. When the two medications are used together, they have an additive antihypertensive effect.

Dosage & Administration

Adult: Per tab contains Atenolol (mg)/Chlorthalidone (mg): 50/25 or 100/25. Initially one tab of 50/12.5 once daily; may increase to one tab of 100/25 based on response.

Renal impairment:
CrCl (ml/min)
15-35 Max dose of Atenolol component: 50 mg/day

Pregnancy & Lactation

This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.

There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.

Pack Size & Price

50's pack Price : ৳150.57

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