Symbion 6/100 Bexicap (Cozycap)
Manufactured by: Beximco Pharmaceuticals Ltd.
Budesonide + Formoterol Fumarate Similar medicine
Symbion 6/100 Bexicap is indicated for
- Asthma
- COPD
Precautions and warnings
Treatment with a combination of budesonide and formoterol should not be started to treat a severe exacerbation or if the patient's asthma is considerably worsening or rapidly deteriorating. It can cause life-threatening paradoxical bronchospasm. When used in patients with cardiovascular illness, notably coronary insufficiency, cardiac arrhythmias, or hypertension, use with caution. Chronic use in patients with advanced age, osteoporosis, poor diet, sedentary lifestyles, or tobacco use may reduce bone mineral content even further. When taken in pediatric patients, it has the potential to slow down growth. Pregnancy and lactation should be avoided in individuals with active or dormant tuberculosis of the respiratory tract, untreated systemic fungal, bacterial, viral, or parasite diseases, or ocular herpes simplex.
Side-effects
- The most common drug related adverse reactions are pharmacologically predictable side effects of beta 2-agonist therapy
- such as tremor
- palpitations. Adverse events which have been associated with Budesonide
- Formoterol are Palpitations
- Candida infections in oropharynx
- Headache
- Tremor
- Coughing
- Hoarseness
- Tachycardia.
Drug Interactions
Concurrent administration of budesonide with a CYP3A4 inhibitor, such as itraconazole, clarithromycin, or erythromycin, may inhibit budesonide metabolism. When used with nonpotassium-sparing diuretics, ECG abnormalities and/or hypokalaemia can occur.
Contraindications
Treatment for status asthmaticus and other acute asthma attacks. Budesonide, Formoterol, or Lactose hypersensitivity.
Mode of actions
Budesonide is a corticosteroid that primarily acts as a glucocorticoid. It works by slowing down protein synthesis, reducing the migration of polymorphonuclear leucocytes/fibroblasts, and reversing capillary permeability to prevent and regulate inflammation. Formoterol fumarate is a 2-adrenergic agonist that is selective. Catalyzing the conversion of adenosine triphosphate to cyclic-3', 5'-adenosine monophosphate (cyclic AMP), promotes bronchodilation and bronchial smooth muscle relaxation.
Dosage & Administration
Asthma Maintenance and reliever therapy: Adults and adolescents (12 years and older) -
As both maintenance and reliever therapy:
Adults and adolescents (12 years and older): The recommended maintenance dose is 1 puff twice daily or 2 puffs once daily. For some patients a maintenance dose of 2 puffs twice daily may be appropriate (for 160/4.5 mcg/inhalation only). Patients should take 1 additional puff as needed in response to symptoms. If symptoms persist after a few minutes, the additional puff should be taken. Not more than 6 puffs should be taken on any single occasion.
Children: The usual maintenance dose is 1-2 puffs once or twice daily. Patients should take 1 additional puff as needed in response to symptoms. If symptoms persist after a few minutes, the additional puff should be taken. Not more than 4 puffs should be taken on any single occasion.
Convicap/cozycap: Maintenance dose: 100 Convicap twice daily. 200 Convicap twice daily. Reliever dose: 1 additional Convicap as needed in response to symptoms. If symptoms persist after a few minutes, an additional Convicap should be taken.
Children-Maintenance dose: 100 Convicap: 1-2 ConviCaps once daily. Reliever dose: 1 additional Convicap as needed in response to symptoms. If symptoms persist after a few minutes, an additional Convicap should be taken.
COPD 200 Convicap: 2 Convicaps twice daily. 400 Convicap: 1 Convicap twice daily
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect even sometimes unable to demonstrate the risk on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required.
Discuss with your doctors and tell them feedback about this medicine.
Pack Size & Price
30's pack Price : ৳210
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