Zidim IV/IM 1gm/vial (Injection)
Manufactured by: Orion Pharma Ltd.
Ceftazidime Similar medicine
Zidim IV/IM is indicated for
- Pneumonie
- mucoviscidose
- septicémie bactérienne
- méningite
- péritonite
- infections de la peau et des structures cutanées
- endométrite
- cellulite pelvienne
- infections des voies respiratoires
- infections des voies urinaires
- neutropénie fébrile
- mélioïdose
- infections des os et des articulations
- infections gynécologiques
- infections des voies biliaires
- endophtalmie
Precautions and warnings
Informez votre médecin de vos antécédents médicaux, surtout si vous souffrez d'une maladie rénale ou de problèmes gastriques/intestinaux.
La ceftazidime peut altérer l'efficacité des vaccinations bactériennes vivantes telles que le vaccin contre la typhoïde. Avant de recevoir des vaccins ou des vaccins, informez votre médecin si vous prenez de la ceftazidime.
Side-effects
- Hypersensibilité
- vertiges
- diarrhée
- nausées
- vomissements
- insuffisance rénale
- éruption cutanée
- érythème polymorphe
- thrombocytopénie
- surinfection
- phloébite et thrombophloébite au site d'injection. Potentiellement mortel : réactions anaphylactiques
- néphrotoxicité
- colite pseudomembraneuse.
Drug Interactions
La néphrotoxicité des aminosides peut être augmentée. Le BCG, la vaccination contre la typhoïde et le picosulfate de Na peuvent avoir une efficacité thérapeutique réduite. L'effet anticoagulant des antagonistes de la vitamine K peut être renforcé (par exemple, la warfarine). Avec le probénécide, il est possible que les taux sériques augmentent.
Contraindications
Évitez ce médicament si vous présentez une hypersensibilité au principe actif des céphalosporines.
Mode of actions
La ceftazidime se lie à une ou plusieurs protéines liant la pénicilline (PBP), ce qui inhibe la dernière étape de transpeptidation de la production de peptidoglycane dans la paroi cellulaire bactérienne, interrompant la biosynthèse et provoquant la mort des cellules bactériennes.
Dosage & Administration
Adultes : La posologie pour adultes de la ceftazidime est de 1 à 6 g par jour 8 ou 12 heures (IM/IV) dans la majorité des infections, 1 g toutes les 8 heures ou 2 g toutes les 12 heures doivent être administrés.
Dans les infections des voies urinaires et de nombreuses infections moins graves, 500 mg ou 1 g toutes les 12 heures sont généralement suffisants.
Dans les infections graves, en particulier chez les patients immunodéprimés, y compris ceux souffrant de neutropénie, 2 g toutes les 8 ou 12 heures doivent être administrés. Lorsqu'il est utilisé comme agent prophylactique en chirurgie prostatique, 1 g doit être administré lors de l'induction de l'anesthésie. Une deuxième dose doit être envisagée au moment du retrait du cathéter.
Nouveau-nés (0 - 2 mois) : 25-60 mg/kg/jour IV Q 12h
Nourrissons et enfants (2 mois - 12 ans) : 30-100 mg/kg/jour IV jusqu'à un maximum de 6 grammes par jour toutes les 8-12h.
Personnes âgées : Dose maximale : 3 g par jour.
Insuffisance rénale : Dose de charge : 1 g ; doses d'entretien basées sur CrCl. Il peut être nécessaire d'augmenter les doses de 50 % en cas d'infections graves. Dialyse péritonéale : la dose de charge est suivie de 500 mg toutes les 24 heures ; peut ajouter de la ceftazidime au liquide de dialyse (généralement 125 à 250 mg pour 2 litres de liquide de dialyse). Hémodialyse : dose de charge administrée, puis 0,5 à 1 g après chaque période de dialyse.
ClCr (ml/min)
31-50 1 g toutes les 12 heures.
16-30 1 g toutes les 24 heures.
6-15 500 mg toutes les 24 heures.
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
1 vial Price : ৳215.81
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Are you looking medicine for Biliary tract infections ?
Ceftazidime is indicated for Pneumonia, Cystic fibrosis, Bacterial septicemia, Meningitis, Peritonitis, Skin and Skin-Structure Infections, Endometritis, Pelvic cellulitis, Respiratory tract infections, Urinary tract infections, Febrile neutropenia, Melioidosis, Bone and Joint Infections, G ynecologic Infections, Biliary tract infections, Endophthalmitis
List of medicines using CeftazidimeGentamicin is indicated for Pneumonia, Cystic fibrosis, Meningitis, Peritonitis, Endocarditis, Susceptible infections, Septicaemia, Pelvic inflammatory disease, Endometritis, Biliary tract infections, Granuloma inguinale, Listeriosis, Gastroenteritis, Plague, Cat scratch disease, Brucellosis, Otitis externa, Surgical infections, Skin infections.
List of medicines using Gentamicin -
Are you looking medicine for Endophthalmitis ?
Ceftazidime is indicated for Pneumonia, Cystic fibrosis, Bacterial septicemia, Meningitis, Peritonitis, Skin and Skin-Structure Infections, Endometritis, Pelvic cellulitis, Respiratory tract infections, Urinary tract infections, Febrile neutropenia, Melioidosis, Bone and Joint Infections, G ynecologic Infections, Biliary tract infections, Endophthalmitis
List of medicines using Ceftazidime
