Xenole 500 (Tablet)
Manufactured by: Square Pharmaceuticals Ltd.
Esomeprazole + Naproxen Similar medicine
Xenole 500 is indicated for
- Artritis reumatoide
- Osteoartritis
- Espondilitis anquilosante
- Rigidez de las articulaciones
Precautions and warnings
Informe a su médico si alguna vez ha tenido asma, enfermedad hepática, sangrado, úlceras, acidez estomacal recurrente, enfermedad cardíaca como antecedentes de ataque cardíaco, presión arterial alta, derrame cerebral, edema, retención de líquidos, niveles bajos de sodio en la sangre, trastornos sanguíneos como anemia, problemas de sangrado o coagulación, pólipos nasales o lupus antes de tomar este medicamento.
Los medicamentos AINE, como el naproxeno, pueden causar dificultades renales en determinadas personas. Si está deshidratado, tiene insuficiencia cardíaca o enfermedad renal, es un adulto mayor o toma ciertos medicamentos, es más probable que tenga problemas. Para evitar la deshidratación, beba muchos líquidos según las recomendaciones de su médico e informe a su médico de inmediato sobre cualquier cambio en la cantidad de orina.
Este medicamento puede causar mareos o somnolencia. Puede marearse o tener sueño si consume alcohol o cannabis. No conduzca, opere maquinaria ni realice ninguna otra actividad que requiera atención hasta que esté seguro de que puede hacerlo de manera segura. Limite su consumo de bebidas alcohólicas. Si consumes cannabis, habla con tu médico.
Este medicamento tiene el potencial de inducir sangrado estomacal. El consumo regular de alcohol y tabaco, especialmente en combinación con esta prescripción, puede aumentar el riesgo de hemorragia estomacal. Para obtener más información, hable con su médico o farmacéutico.
Side-effects
- En general
- las reacciones adversas más comunes en los ensayos clínicos (>5%): gastritis erosiva
- dispepsia
- gastritis
- diarrea
- úlcera gástrica
- dolor abdominal superior
- náuseas
- etc.
Drug Interactions
Aliskiren, inhibidores de la ECA como captopril y lisinopril, bloqueadores de los receptores de angiotensina II como valsartán y losartán, corticosteroides como prednisona, litio, metotrexato, especialmente terapia en dosis altas, y rifampicina son algunos de los productos que pueden interactuar con este medicamento.
Cuando se combina con otros medicamentos que pueden causar sangrado, este medicamento puede aumentar el riesgo de sangrado. Los medicamentos antiplaquetarios como el clopidogrel, así como los "anticoagulantes" como el dabigatrán/enoxaparina/warfarina, son ejemplos.
Algunos productos requieren que el cuerpo absorba adecuadamente el ácido del estómago. Debido a que el esomeprazol reduce el ácido del estómago, puede afectar la eficacia de estos medicamentos. Entre los productos afectados se encuentran atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirina y ciertos antimicóticos azólicos como itraconazol, ketoconazol y posaconazol.
Contraindications
• Hipersensibilidad a cualquiera de los ingredientes de Progesic o bencimidazoles sustituidos.
• Asma, urticaria u otras respuestas alérgicas después de usar aspirina u otros medicamentos antiinflamatorios no esteroides.
• En el caso de cirugía de injerto de derivación de arteria coronaria (CABG), utilizar durante el período perioperatorio.
• Una señora que se encuentra en una etapa avanzada de su embarazo.
Mode of actions
Un AINE prototípico es el naproxeno, un derivado del ácido propiónico. Inhibe las enzimas ciclooxigenasa-1 y -2 (COX-1 y -2) de manera reversible, lo que resulta en una reducción en la síntesis de precursores de prostaglandinas. Posee propiedades antiinflamatorias, analgésicas y antipiréticas, además de inhibir la agregación plaquetaria.
El esomeprazol es un inhibidor de la bomba de protones (IBP) que inhibe la H+/K+ ATPasa en la célula parietal gástrica, suprimiendo la producción de ácido gástrico. Es el isómero S del omeprazol.
Dosage & Administration
Artritis reumatoide, osteoartritis, espondilitis alquilosante y dismenorrea: 375 o 500 mg, un comprimido dos veces al día.
Pregnancy & Lactation
Este medicamento no está permitido durante el embarazo. No lo utilice si está embarazada. Puede absorberse a través de la piel y los pulmones y puede dañar los órganos del feto y causar discapacidades congénitas. Control de la natalidad estricto y eficaz durante el tratamiento y durante seis meses después de suspender este medicamento. Si queda embarazada, deje de tomar este medicamento y hable con su médico de inmediato.
No existe información específica sobre si este medicamento pasa a la leche materna o no. Teniendo en cuenta los posibles riesgos para los niños, no se recomienda amamantar mientras se utiliza este medicamento y al menos dos semanas después de la última dosis. Consulte a su médico antes de amamantar.
Pack Size & Price
30's pack Price : ৳300
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