Drug Interactions

Some medicines—such as antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim, and sulphonamides—can lower the amount of folate in your blood. They can also reduce the blood levels of phenytoin.

Contraindications

Do not use this product if you are allergic to any of its ingredients. Folic Acid should not be taken if you have untreated vitamin B12 (cobalamin) deficiency.

Mode of actions

Folic acid helps the body make DNA and supports the production of healthy red blood cells. In the body, it is changed into its active form (tetrahydrofolic acid) by an enzyme called dihydrofolate reductase, mainly in the liver and plasma. For women who could become pregnant, folic acid is important because it helps prevent birth defects of the brain and spine (neural tube defects). Pregnant women need higher amounts of folic acid.

Dosage & Administration

Adult: PO Folate-deficient megaloblastic anaemia 5 mg/day for 4 mth, up to 15 mg/day in malabsorption states. Prophylaxis of megaloblastic anaemia in pregnancy 0.2-0.5 mg/day. Prophylaxis of neural tube defect in pregnancy 4 or 5 mg/day. Supplement for women of child-bearing potential 0.4 mg/day.

Pregnancy & Lactation

Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy and there is not enough evidence of risk in later trimesters.

Pack Size & Price