Cardobis Plus 2.5 mg + 6.25 mg (Tablet)
Manufactured by: Eskayef Bangladesh Ltd.
Bisoprolol + Hydrochlorothiazide Similar medicine
Cardobis Plus is indicated for
- Hipertensão
- Insuficiência cardíaca congestiva
- hipertensão
- angina de peito
Precautions and warnings
Certas pessoas que tomam diuréticos tiazídicos podem desenvolver hiperuricemia ou gota grave. Boca seca, sede, fraqueza, letargia, sonolência, inquietação, dores ou cãibras musculares, cansaço muscular, hipotensão, oligúria, taquicardia e distúrbios gastrointestinais, como náuseas e vômitos, são todas indicações ou sintomas de alerta de desequilíbrio hidroeletrolítico. Pode ocorrer hipocalemia. Se quiser parar de tomar esta terapia combinada, faça-o gradualmente durante um período de duas semanas. Os pacientes devem ser monitorados de perto.
Side-effects
- Tontura
- dor de cabeça
- fadiga
- bradicardia. Náuseas
- vómitos
- diarreia ou obstipação
- desconforto estomacal
- ardor ocular ligeiro
- fotofobia
- queratite
- diminuição da capacidade sexual. Distúrbios gastrointestinais
- dispneia
- extremidades frias
- insônia
- alucinações
- sonolência e alterações de humor. Potencialmente fatal: bloqueio AV
- bradicardia. Raro
- mas pode ocorrer em pacientes com doença cardíaca preexistente. Inclui broncoespasmo grave
- hipoglicemia
- hipotensão
- hipotensão ortostática
- bradiarritmias. 'Fenômeno de rebote' levando a angina instável ou IM após retirada súbita.
Drug Interactions
Este medicamento combinado pode aumentar os efeitos de outros medicamentos anti-hipertensivos usados ao mesmo tempo. Outros medicamentos betabloqueadores não devem ser tomados com esta terapia combinada. Pacientes em uso de medicamentos depletores de catecolaminas, como reserpina ou guanetidina, devem ser constantemente monitorados porque a ação bloqueadora beta-adrenérgica adicional do fumarato de bisoprolol pode causar uma redução excessiva na atividade simpática. Se a terapia com clonidina for interrompida, recomenda-se que este medicamento combinado seja interrompido por muitos dias antes de a clonidina ser interrompida. Quando depressores cardíacos ou inibidores da condução AV, como antagonistas do cálcio (especialmente das classes feniletilamina [verapamil] e benzotiazepina [diltiazem]) ou medicamentos antiarrítmicos, como a disopiramida, são administrados concomitantemente, esta medicação combinada deve ser usada com cautela. Os betabloqueadores e os glicosídeos digitálicos atrasam a condução atrioventricular e diminuem a frequência cardíaca. O uso simultâneo pode colocar você em risco de bradicardia.
Contraindications
Choque cardiogênico, insuficiência cardíaca evidente, bloqueio AV de segundo ou terceiro grau, bradicardia sinusal significativa, anúria e hipersensibilidade a qualquer componente deste medicamento ou outros produtos farmacêuticos derivados de sulfonamida são contra-indicações.
Mode of actions
Fumarato de bisoprolol / hidroclorotiazida é uma pílula de combinação fixa que contém fumarato de bisoprolol, um bloqueador dos receptores beta adrenérgicos, e hidroclorotiazida, um diurético tiazídico.
O fumarato de bisoprolol, um inibidor cardiosseletivo dos receptores beta(1)-adrenérgicos, não tem atividade simpaticomimética ou estabilizadora de membrana inerente em doses terapêuticas, mas inibe os receptores beta(2)-adrenérgicos e tem um impacto cronotrópico negativo.
O diurético tiazídico hidroclorotiazida inibe a reabsorção de Na nos túbulos renais distais, resultando em aumento da excreção de Na+, água, bem como de íons K+ e H+.
Dosage & Administration
Adulto: PO Inicial: comprimido de 2,5 mg/6,25 mg uma vez ao dia.
Aumento com base na resposta clínica em 2 semanas. Máximo: bisoprolol 20 mg/hidroclorotiazida 12,5 mg uma vez ao dia.
Pregnancy & Lactation
Este medicamento não é permitido durante a gravidez. Não use se estiver grávida. Pode ser absorvido pela pele e pelos pulmões, podendo danificar os órgãos do feto e causar deficiências congênitas. Controle de natalidade rigoroso e eficaz durante o tratamento e por seis meses após a interrupção do medicamento. Se engravidar, pare de tomar este medicamento e fale com o seu médico imediatamente.
Não há informações específicas sobre se este medicamento passa ou não para o leite materno. Considerando os possíveis riscos para as crianças, não é recomendada a amamentação durante o uso deste medicamento e pelo menos duas semanas após a última dose. Consulte seu médico antes de amamentar.
Pack Size & Price
Price : ৳
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