C-quin 50 mg/5ml (Syrup)
Manufactured by: Opsonin Pharma Limited
Chloroquine Phosphate Similar medicine
C-quin is indicated for
- Artritis reumatoide
- Malaria
- Lupus eritematoso sistémico
- LES
- Amebiasis
Precautions and warnings
No use este medicamento en personas con psoriasis, enfermedades de la sangre o del sistema nervioso, miastenia gravis, problemas hepáticos o renales, deficiencia de G6PD, epilepsia o en niños. También se debe evitar durante el embarazo y la lactancia. Cuando administre este medicamento por vía intravenosa, infúndalo lentamente para reducir el riesgo de problemas cardíacos.
Side-effects
- Retinopatía
- caída del cabello
- fotosensibilidad
- tinnitus
- miopatía (terapia a largo plazo). Psicosis
- convulsiones
- leucopenia y rara vez anemia aplásica
- hepatitis
- trastornos gastrointestinales
- mareos
- hipopotasemia
- dolor de cabeza
- prurito
- urticaria
- dificultad en la acomodación visual. Potencialmente mortal: paro cardíaco y respiratorio
- colapso CV
- convulsiones
- coma.
Drug Interactions
Tomar fenilbutazona al mismo tiempo puede aumentar la probabilidad de sufrir erupciones cutáneas, reducir la eficacia de la neostigmina y la piridostigmina y reducir la cantidad de ampicilina que absorbe su cuerpo. La cimetidina puede aumentar la cantidad de cloroquina en la sangre al retardar su descomposición.
**Riesgos graves:**
- Cuando la cloroquina se toma con halofantrina u otros medicamentos que afectan el ritmo cardíaco (como la amiodarona), existe una mayor probabilidad de sufrir arritmias cardíacas peligrosas.
- También existe un mayor riesgo de sufrir convulsiones cuando se toma cloroquina con mefloquina.
- Los antiácidos pueden disminuir la absorción de la cloroquina, por lo que se deben tomar con al menos 4 horas de diferencia entre sí.
- En raras ocasiones, puede producirse una reacción cutánea grave (síndrome de Stevens-Johnson) si se toma cloroquina con pirimetamina o sulfadoxina.
- Tomar quinacrina con cloroquina puede aumentar el riesgo de efectos secundarios.
Contraindications
No lo use si tiene alergia al medicamento, infección por P. falciparum resistente posible o confirmada, porfiria, problemas de retina o si está tomando otros medicamentos que son dañinos para el hígado.
Mode of actions
La cloroquina se usa para prevenir la malaria y tratar ataques repentinos de malaria. Funciona bien contra los estadios sanguíneos de *Plasmodium vivax*, *P. malariae* y *P. falciparum*. El fármaco eleva el pH dentro de la vacuola alimentaria del parásito, lo que altera la digestión de la hemoglobina y afecta la forma en que el parásito produce proteínas. La cloroquina también es útil en el tratamiento de la amebiasis fuera de los intestinos. Para la artritis reumatoide (AR), tanto la cloroquina como el fármaco similar hidroxicloroquina pueden ayudar a ralentizar el progreso de la enfermedad, siendo la hidroxicloroquina más eficaz.
Dosage & Administration
Adulto: VO Malaria aguda Como base: Inicial: 600 mg, luego 300 mg 6-8 horas después el día 1. Continuar con 300 mg/día los días 2 y 3.
Profilaxis contra la malaria Como base: 300 mg/semana, comenzando 1 semana antes de la exposición, continuar semanalmente y durante al menos 4 semanas después de la exposición.
Discoide y LES; Artritis reumatoide Como base: Inicial: 150 mg/día. Máximo: 2,5 mg/kg/día.
Amebiasis hepática Como base: con emetina o deshidroemetina: 600 mg/día durante 2 días y luego 300 mg/día durante 2-3 semanas.
IV Malaria grave Como base: 25 mg/kg administrados en varias infusiones durante 30-32 h.
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso en el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario a pesar de los riesgos potenciales.
Las madres con un bebé recién nacido que han usado este medicamento durante los últimos 3 meses de embarazo rara vez presentan síntomas que incluyen somnolencia, rigidez o temblores musculares, problemas para alimentarse o respirar, y llanto constante. Si nota alguno de estos síntomas en su bebé, especialmente durante el primer mes, informe al médico de inmediato.
Este medicamento pasa a la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
60ml bot Price : ৳
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