Imilast 500 500 mg + 500 mg (IV/IM Injection)
Manufactured by: Bio Pharma Laboratories Ltd.
Cilastatin + Imipenem Similar medicine
Imilast 500 is indicated for
- Fibrosis quística
- Septicemia bacteriana
- Endocarditis
- Infecciones susceptibles
- Infecciones del tracto respiratorio inferior
- Gonorrea
- Infecciones de la piel y de las estructuras de la piel
- Infecciones del tracto urinario
- Infecciones de huesos y articulaciones
- Profilaxis quirúrgica
Precautions and warnings
Tenga cuidado al administrar este medicamento a pacientes alérgicos a otros antibióticos betalactámicos, ya que también podrían reaccionar a este medicamento. Úselo con precaución en personas con afecciones como epilepsia o problemas renales o hepáticos. Tenga especial cuidado si la paciente está embarazada o amamantando.
Side-effects
- Erupciones cutáneas
- urticaria
- eosinofilia
- fiebre
- náuseas
- vómitos
- diarrea
- decoloración de dientes o lengua y alteración del gusto. Eritema multiforme
- dermatitis exfoliativa. Puede producirse dolor y tromboflebitis en el lugar de la inyección. Potencialmente fatal: síndrome de Stevens-Johnson
- necrólisis epidérmica tóxica.
Drug Interactions
Tomar probenecid al mismo tiempo que cilastatina puede hacer que la cilastatina permanezca en el cuerpo por más tiempo. El uso de cilastatina junto con ganciclovir puede aumentar el riesgo de sufrir convulsiones.
Mode of actions
El imipenem es un antibiótico potente que mata muchos tipos de bacterias impidiéndoles formar sus paredes celulares. Funciona bien porque no es descompuesto por ciertas enzimas (llamadas ?-lactamasas) que muchas bacterias utilizan para protegerse. La cilastatina es un medicamento que bloquea una enzima en los riñones (llamada deshidropeptidasa I). Cuando el imipenem se administra junto con cilastatina, ayuda a evitar que el imipenem se descomponga en los riñones y protege contra el daño renal. Ambos medicamentos se administran en forma de sales de sodio.
Dosage & Administration
Adultos: IV Infecciones susceptibles Como imipenem: 1-2 g/día en dosis divididas 6-8 horas. Profilaxis quirúrgica Como imipenem: 1 g en la inducción del anestésico, seguido de 1 g 3 horas después. Si es necesario, se pueden administrar dosis adicionales de 500 mg a las 8 y 16 horas después de la inducción.
Niño: >40 kg: igual que la dosis de adulto. >3 meses y
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso en el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario a pesar de los riesgos potenciales.
Las madres con un bebé recién nacido que han usado este medicamento durante los últimos 3 meses del embarazo rara vez presentan síntomas que incluyen somnolencia, rigidez o temblores musculares, problemas para alimentarse o respirar, y llanto constante. Si nota alguno de estos síntomas en su bebé, especialmente durante el primer mes, informe al médico de inmediato.
Este medicamento pasa a la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
Price : ৳
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