Dapsone 100mg (Tablet)
Manufactured by: EDCL (Dhaka)
Dapsone Similar medicine
Dapsone is indicated for
- Pneumonia
- Acne
- Leprosy
- Dermatitis herpetiformis
Precautions and warnings
G6PD deficiency, methemoglobinemia, or hemoglobin M. Check blood counts and liver function regularly. Take extra care during pregnancy and breastfeeding.
Side-effects
- Anaemia
- peripheral neuropathy
- haemolysis
- methaemoglobinaemia (dose-related)
- nephrotic syndrome
- psychological changes
- hepatitis. Others: Nausea
- vomiting
- anorexia
- headache
- maculopapular rash
- toxic epidermal necrolysis
- Stevens-Johnson syndrome. Topical: Dryness
- redness
- oiliness
- peeling at application site. Potentially Fatal: Agranulocytosis
- serious cutaneous hypersensitivity reactions
- exfoliative dermatitis.
Drug Interactions
When dapsone is taken with rifampicin, its level in the blood goes down. If dapsone is taken with probenecid or trimethoprim, its blood level goes up. Dapsone also works against (antagonizes) clofazimine.
Mode of actions
Dapsone works by stopping bacteria from using PABA, which they need to make folic acid. This blocks the bacteria from making folic acid, which is important for their growth.
Dosage & Administration
Adult: PO Prophylaxis of Pneumocystis (carinii) jiroveci pneumonia50 mg/day (w/ pyrimethamine once wkly).
Multibacillary leprosy 100 mg/day (w/ clofazimine and rifampicin in different dosage regimens) for 12 mth.
Paucibacillary leprosy 100 mg/day (w/ rifampicin once mthly) for 6 mth.
Dermatitis herpetiformis Initial: 50 mg/day, up to 300 mg/day if needed. T
Pregnancy & Lactation
Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.
Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.
This medicine passes into breast milk. Talk to your doctor before breastfeeding.
Pack Size & Price
Price : ৳
Similar medicine
Manufactured by: G. A. Company Ltd.
Manufactured by: EDCL (Dhaka)
Manufactured by: EDCL (Dhaka)
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