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Cosarin (Tablet)

Manufactured by: Opsonin Pharma Limited

Diacerein + Glucosamine Sulphate Similar medicine

Cosarin is indicated for Rheumatoid arthritis, Osteoarthritis, Chronic low back pain

Precautions and warnings

Caution should be practiced when administering Diacerein + Glucosamine Sulphate in those patients who are allergic to Glucosamine and/or Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. Before taking Diacerein + Glucosamine Sulphate complete blood count, liver function and urinalysis should be monitored regularly.

Side-effects

Diarrhea, constipation,
epigastric pain, heart burn, nausea, vomiting, headache, skin rashes, drowsiness, intense yellow coloring of urine.

Drug Interactions

Diacerein: Decreased absorption with aluminium and/or magnesium hydroxide antacids. Increased risk of diarrhoea with laxatives, antibiotics. Avoid co-admin with fibres and phytates.

Glucosamine: May reduce effect of antidiabetic agents, doxorubicin, etoposide, tenoposide. May enhance anticoagulant activity of warfarin.

Contraindications

Absorption of Diacerein is reduced if taken with aluminium and/or magnesium hydroxide antacid. Diacerein also increases risk of diarrhea if taken with laxatives, antibiotics. Avoid co-administration with fibers and phytic acids. Diacerein has shown hypersensitivity to anthraquinone derivatives.

Mode of actions

Diacerein is an anthraquinone derivative that has been used in osteoarthritis. It is thought to act via inhibition of interleukin-1?.Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.

Dosage & Administration

Adults and children over 12 years and older:
1 tablet twice daily (12 hourly) taken with food.

Pregnancy & Lactation

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

6x5's pack Price : ৳316.5