Eprox Plus 20 mg + 500 mg (Tablet)
Manufactured by: Euro Pharma Ltd.
Esomeprazole + Naproxen Similar medicine
Eprox Plus is indicated for
- Artritis reumatoid
- Osteoartritis
- Ankylosing spondylitis
- Kekakuan sendi
Precautions and warnings
Beritahu dokter jika Anda pernah menderita asma, penyakit liver, pendarahan, maag, sakit maag berulang, penyakit jantung seperti riwayat serangan jantung, tekanan darah tinggi, stroke, edema, retensi cairan, kadar natrium darah rendah, kelainan darah seperti anemia, masalah pendarahan atau pembekuan darah, polip hidung, atau lupus sebelum meminum obat ini.
Obat NSAID, seperti naproxen, dapat menyebabkan gangguan ginjal pada orang tertentu. Jika Anda mengalami dehidrasi, mengalami gagal jantung atau penyakit ginjal, berusia lanjut, atau mengonsumsi obat-obatan tertentu, kemungkinan besar Anda akan mengalami masalah tersebut. Untuk menghindari dehidrasi, minumlah banyak cairan seperti yang disarankan oleh dokter Anda, dan segera laporkan setiap perubahan jumlah urin ke dokter Anda.
Obat ini dapat menyebabkan pusing atau mengantuk. Anda mungkin pusing atau mengantuk jika mengonsumsi alkohol atau ganja. Jangan mengemudi, mengoperasikan mesin, atau melakukan aktivitas lain apa pun yang memerlukan perhatian sampai Anda yakin dapat melakukannya dengan aman. Batasi asupan minuman beralkohol. Jika Anda menggunakan ganja, bicarakan dengan dokter Anda.
Obat ini berpotensi menyebabkan pendarahan lambung. Penggunaan alkohol dan tembakau secara rutin, terutama jika dikombinasikan dengan resep ini, dapat meningkatkan risiko pendarahan lambung. Untuk informasi lebih lanjut, bicarakan dengan dokter atau apoteker Anda.
Side-effects
- Secara umum
- Reaksi merugikan yang paling umum dalam uji klinis (>5%): gastritis erosif
- dispepsia
- maag
- diare
- tukak lambung
- sakit perut bagian atas
- mual
- dll.
Drug Interactions
Aliskiren, ACE inhibitor seperti kaptopril dan lisinopril, penghambat reseptor angiotensin II seperti valsartan dan losartan, kortikosteroid seperti prednison, litium, metotreksat, terutama terapi dosis tinggi, dan rifampisin adalah beberapa produk yang dapat berinteraksi dengan obat ini.
Jika dikombinasikan dengan obat lain yang dapat menyebabkan perdarahan, obat ini dapat meningkatkan risiko perdarahan. Obat antiplatelet seperti clopidogrel, serta "pengencer darah" seperti dabigatran/enoxaparin/warfarin, adalah contohnya.
Beberapa produk memerlukan asam lambung agar dapat diserap dengan baik oleh tubuh. Karena esomeprazole mengurangi asam lambung, hal ini dapat memengaruhi efektivitas kerja obat-obatan ini. Atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, dan antijamur azole tertentu seperti itraconazole, ketoconazole, dan posaconazole termasuk di antara produk yang terkena dampak.
Contraindications
• Hipersensitif terhadap salah satu bahan Progesic atau benzimidazol penggantinya.
• Asma, urtikaria, atau respons alergi lainnya setelah penggunaan aspirin atau obat antiinflamasi nonsteroid lainnya
• Dalam kasus operasi cangkok bypass arteri koroner (CABG), gunakan selama periode perioperatif.
• Seorang wanita yang kehamilannya terlambat.
Mode of actions
NSAID prototipe adalah naproxen, turunan asam propionat. Ini menghambat enzim siklooksigenase-1 dan -2 (COX-1 dan -2) secara reversibel, mengakibatkan penurunan sintesis prekursor prostaglandin. Ia memiliki sifat anti-inflamasi, analgesik, dan antipiretik, serta menghambat agregasi trombosit.
Esomeprazole adalah penghambat pompa proton (PPI) yang menghambat H+/K+ ATPase di sel parietal lambung, menekan keluaran asam lambung. Itu adalah isomer S omeprazol.
Dosage & Administration
Artritis Reumatoid, Osteoartritis, Alkylosing Spondylitis, dan dismenorea: 375 atau 500 mg, satu tablet dua kali sehari.
Pregnancy & Lactation
Obat ini tidak diperbolehkan selama kehamilan. Jangan gunakan jika Anda sedang hamil. Dapat diserap melalui kulit dan paru-paru sehingga dapat merusak organ tubuh anak Anda yang belum lahir dan menyebabkan cacat bawaan. Alat kontrasepsi yang efektif dan ketat selama pengobatan dan selama enam bulan setelah menghentikan obat ini. Jika Anda hamil, hentikan penggunaan obat ini dan segera diskusikan dengan dokter Anda.
Belum ada informasi spesifik apakah obat ini masuk ke dalam ASI atau tidak. Mengingat kemungkinan risiko pada anak-anak, menyusui saat menggunakan obat ini tidak dianjurkan dan setidaknya dua minggu setelah dosis terakhir. Konsultasikan dengan dokter Anda sebelum menyusui.
Pack Size & Price
Price : ৳
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