Napexa 20 mg + 375 mg (Tablet)
Manufactured by: Unimed & Unihealth Manufacturers Ltd.
Esomeprazole + Naproxen Similar medicine
Napexa is indicated for
- Rheumatoide Arthritis
- Osteoarthritis
- Morbus Bechterew
- Gelenksteifheit
Precautions and warnings
Informieren Sie Ihren Arzt, wenn Sie jemals Asthma, Lebererkrankungen, Blutungen, Geschwüre, wiederkehrendes Sodbrennen, Herzerkrankungen wie Herzinfarkt, Bluthochdruck, Schlaganfall, Ödeme, Flüssigkeitsretention, niedrige Natriumspiegel im Blut, Bluterkrankungen wie Anämie, Blutungen oder Gerinnungsprobleme, Nasenpolypen oder Lupus hatten, bevor Sie dieses Medikament einnehmen.
NSAID-Medikamente wie Naproxen können bei bestimmten Menschen zu Nierenproblemen führen. Wenn Sie dehydriert sind, an Herzversagen oder einer Nierenerkrankung leiden, ein älterer Erwachsener sind oder bestimmte Medikamente einnehmen, ist die Wahrscheinlichkeit größer, dass Sie Probleme haben. Um eine Dehydrierung zu vermeiden, trinken Sie gemäß den Anweisungen Ihres Arztes viel Flüssigkeit und informieren Sie Ihren Arzt umgehend über etwaige Veränderungen der Urinmenge.
Dieses Medikament kann Schwindel oder Schläfrigkeit verursachen. Wenn Sie Alkohol oder Cannabis konsumieren, kann es zu Schwindel oder Schläfrigkeit kommen. Führen Sie kein Fahrzeug, bedienen Sie keine Maschinen und üben Sie keine andere Tätigkeit aus, die Aufmerksamkeit erfordert, bis Sie sicher sind, dass Sie dies sicher tun können. Beschränken Sie den Konsum alkoholischer Getränke. Wenn Sie Cannabis konsumieren, sprechen Sie mit Ihrem Arzt.
Dieses Arzneimittel kann Magenblutungen auslösen. Der regelmäßige Konsum von Alkohol und Tabak, insbesondere in Kombination mit diesem Rezept, kann das Risiko von Magenblutungen erhöhen. Für weitere Informationen sprechen Sie mit Ihrem Arzt oder Apotheker.
Side-effects
- Im Allgemeinen sind die häufigsten Nebenwirkungen in klinischen Studien (>5 %): erosive Gastritis
- Dyspepsie
- Gastritis
- Durchfall
- Magengeschwür
- Oberbauchschmerzen
- Übelkeit usw.
Drug Interactions
Aliskiren, ACE-Hemmer wie Captopril und Lisinopril, Angiotensin-II-Rezeptorblocker wie Valsartan und Losartan, Kortikosteroide wie Prednison, Lithium, Methotrexat, insbesondere Hochdosistherapie, und Rifampin sind einige der Produkte, die mit diesem Arzneimittel interagieren können.
In Kombination mit anderen Medikamenten, die Blutungen verursachen können, kann dieses Medikament das Blutungsrisiko erhöhen. Beispiele hierfür sind Thrombozytenaggregationshemmer wie Clopidogrel sowie „Blutverdünner“ wie Dabigatran/Enoxaparin/Warfarin.
Manche Produkte benötigen Magensäure, um ausreichend vom Körper aufgenommen zu werden. Da Esomeprazol die Magensäure reduziert, kann es die Wirksamkeit dieser Medikamente beeinflussen. Zu den betroffenen Produkten gehören Atazanavir, Erlotinib, Nelfinavir, Pazopanib, Rilpivirin und bestimmte Azol-Antimykotika wie Itraconazol, Ketoconazol und Posaconazol.
Contraindications
• Überempfindlichkeit gegen einen der Inhaltsstoffe von Progesic oder substituierte Benzimidazole.
• Asthma, Urtikaria oder andere allergische Reaktionen nach der Einnahme von Aspirin oder anderen nichtsteroidalen entzündungshemmenden Arzneimitteln
• Im Falle einer Koronararterien-Bypass-Operation (CABG) während der perioperativen Phase verwenden.
• Eine Frau, die spät schwanger ist.
Mode of actions
Ein prototypisches NSAID ist Naproxen, ein Propionsäurederivat. Es hemmt die Enzyme Cyclooxygenase-1 und -2 (COX-1 und -2) auf reversible Weise, was zu einer Verringerung der Prostaglandin-Vorläufersynthese führt. Es besitzt entzündungshemmende, schmerzstillende und fiebersenkende Eigenschaften und hemmt die Blutplättchenaggregation.
Esomeprazol ist ein Protonenpumpenhemmer (PPI), der die H+/K+-ATPase in der Belegzelle des Magens hemmt und so die Magensäureproduktion unterdrückt. Es ist das Omeprazol-S-Isomer.
Dosage & Administration
Rheumatoide Arthritis, Osteoarthritis, Alkylosierende Spondylitis und Dysmenorrhoe: 375 oder 500 mg, eine Tablette zweimal täglich.
Pregnancy & Lactation
Dieses Arzneimittel ist während der Schwangerschaft nicht erlaubt. Verwenden Sie es nicht, wenn Sie schwanger sind. Es kann über die Haut und die Lunge aufgenommen werden und kann die Organe Ihres ungeborenen Kindes schädigen und zu angeborenen Behinderungen führen. Strenge wirksame Empfängnisverhütung während der Behandlung und für sechs Monate nach Absetzen dieses Arzneimittels. Wenn Sie schwanger werden, beenden Sie die Einnahme dieses Arzneimittels und sprechen Sie sofort mit Ihrem Arzt.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel in die Muttermilch übergeht oder nicht. Angesichts der möglichen Risiken für die Kinder wird das Stillen während der Anwendung dieses Arzneimittels und mindestens zwei Wochen nach der letzten Dosis nicht empfohlen. Konsultieren Sie vor dem Stillen Ihren Arzt.
Pack Size & Price
Price : ৳
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