Precautions and warnings

If you have liver or kidney problems, your doctor should monitor you closely. Children’s weight should be checked regularly. Tell your doctor right away if you have any allergic reactions. Do not stop taking this medicine suddenly unless you develop serious skin reactions. This medicine might make it unsafe to drive or use machines. Use caution if you are pregnant or breastfeeding.

Drug Interactions

Some drugs, like phenytoin, carbamazepine, phenobarbitone, primidone, rifampicin, and the combination of ethinyloestradiol and levonorgestrel, speed up metabolism by increasing the activity of certain enzymes. On the other hand, sodium valproate slows down metabolism.

Mode of actions

Lamotrigine works by blocking certain sodium channels in the brain. This helps to steady the nerve cells and reduces the abnormal release of chemicals like glutamate and aspartate, which can cause and spread epileptic seizures.

Dosage & Administration

Oral
Epilepsy
Adult: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100-200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily.

Child: >12 yr: Initially, 25 mg once daily for 2 wk followed by 50 mg once daily for 2 wk; thereafter, increase the dose by a max of 50-100 mg every 1-2 wk to usual maintenance doses of 100 -200 mg daily, as a single dose or in 2 divided doses. Some patients may require up to 500 mg daily.

Pregnancy & Lactation

Although animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in pregnant women, but during pregnancy, this medicine can be used just when definitely required despite potential risks.

Mothers with a newborn baby who have used this drug during the last 3 months of pregnancy may seldom create symptoms including drowsiness, muscle stiffness or shakiness, feeding or breathing troubles, constant crying. If you notice any of these symptoms of your baby's particularly during their first month, tell the doctor immediately.

This medicine passes into breast milk. Talk to your doctor before breastfeeding.

Pack Size & Price