Merocil 1 gm/vial (Injection)
Manufactured by: Pharmacil Ltd.
Meropenem Similar medicine
Merocil is indicated for
- 囊性纖維化、腹腔內感染、腦膜炎、皮膚和皮膚結構感染、糖尿病足感染
Precautions and warnings
在使用這種藥物之前，請告知您的醫生或藥劑師您以前患有的任何醫療狀況，特別是如果您患有癲癇、頭部受傷或腫瘤。
頭痛、皮膚麻木或刺痛以及癲癇發作都是這種藥物可能產生的副作用。 在您確定可以安全地進行之前，請勿駕駛、操作機器或從事任何需要保持警覺或視力清晰的活動。
這種藥物的某些版本含有鈉。 如果您正在限製鹽的飲食，或者您的病情如果攝入額外的鹽可能會變得更糟，請諮詢您的醫生。
美羅培南可能會損害活細菌疫苗接種的效果。 在進行任何免疫接種或疫苗接種之前，請告訴您的醫生您正在服用美羅培南。
Side-effects
- 腹瀉、噁心、嘔吐、腹痛；頭痛;便秘;皮疹，瘙癢，蕁麻疹;呼吸暫停；靜脈炎、血栓性靜脈炎、注射部位腫脹和疼痛； LFT 紊亂（可能導致血清轉氨酶、鹼性磷酸酶、乳酸脫氫酶升高）。 罕見：多形紅斑；嗜酸性粒細胞增多、血小板減少、白細胞減少、中性粒細胞減少；據報導，患有潛在中樞神經系統疾病或腎功能不全的患者出現癲癇發作和中樞神經系統影響。 潛在致命：過敏反應；偽膜性結腸炎;史蒂文斯-約翰遜綜合症。
Drug Interactions
丙戊酸和類似藥物是可能與該藥物相互作用的產品的例子。
Mode of actions
美羅培南是一種碳青黴烯內酰胺抗生素，通過與多種青黴素結合蛋白結合來抑制 gm+ve 和 gm-ve 細菌 (PBP) 中細菌細胞壁的形成。
Dosage & Administration
成人：IV 敏感感染 0.5-1 g，每 8 小時一次。 腦膜炎 2 g，8 小時一次。 囊性纖維化 最多 2 g，每 8 小時一次。 皮膚感染 500 mg，每 8 小時一次。 糖尿病足；腹腔內感染 1 g，8 小時一次。
兒童：3個月至12歲。 每 8 小時靜脈注射 10 至 40 mg/kg，具體取決於感染的類型和嚴重程度、病原體的敏感性以及患者的狀況。
腹腔內感染：每 8 小時 20 mg/kg。
囊性纖維化（4-18歲）：每8小時25-40 mg/kg。
腦膜炎：40 mg/kg IV，每 8 小時一次。
體重50公斤以上兒童：按成人劑量。
腎功能損害：
CrCl (毫升/分鐘)
26-50 常用劑量，每 12 小時一次。
10-25 每小時 12 小時，常用劑量的一半。
Pregnancy & Lactation
雖然動物生殖研究顯示出不良影響，甚至有時無法證明對胎兒的風險，並且在孕婦中沒有充分和良好對照的研究，但在懷孕期間，這種藥物可以在確實需要時使用。
與您的醫生討論並告訴他們有關該藥物的反饋。
目前還沒有關於這種藥物是否通過母乳傳染給嬰兒的具體信息。 母乳喂養前請與您的醫生討論。
Pack Size & Price
Price : ৳
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