Cefex 125mg/5ml (Powder for Suspension)
Manufactured by: Doctor's Chemicals Works Ltd.
Cephalexin Similar medicine
Cefex is indicated for
- Pneumonie
- otite moyenne
- endocardite bactérienne
- pharyngite streptococcique
- cellulite
- infections des voies respiratoires
- infections des voies urinaires
- infections des os et des articulations
- infections des voies génito-urinaires
- prostatite aiguë
Precautions and warnings
Informez votre médecin de vos antécédents médicaux, en particulier si vous souffrez d'une maladie rénale ou d'une maladie de l'estomac, avant d'utiliser ce médicament.
La version liquide de ce produit peut contenir du sucre. Si vous souffrez de diabète, vous devez faire preuve de prudence. Consultez votre médecin ou votre pharmacien pour obtenir des conseils sur la façon d'utiliser ce médicament en toute sécurité.
La céphalexine peut altérer l'efficacité des vaccinations bactériennes vivantes telles que le vaccin contre la typhoïde. Avant de vous faire vacciner ou vacciner, informez votre médecin que vous prenez de la céphalexine.
Side-effects
- Douleur au site d'injection ; hypersensibilité; Troubles gastro-intestinaux ; éosinophilie
- neutropénie
- leucopénie
- thrombocytopénie. Potentiellement mortel : réactions anaphylactiques ; néphrotoxicité.
Drug Interactions
L'acidose lactique peut être mortelle si elle est utilisée en même temps que la metfromine.
L'effet anticoagulant des antagonistes de la vitamine K peut être renforcé (par exemple, la warfarine). Les diurétiques puissants (par exemple, l'acide éthacrynique, le furosémide) et d'autres antibiotiques potentiellement néphrotoxiques augmentent le risque de néphrotoxicité (par exemple, les aminosides, la polymyxine, la colistine).
Lorsque des anticoagulants oraux et le temps de Quick sont utilisés conjointement, le temps de Quick peut être prolongé.
Contraindications
Évitez ce médicament si vous présentez une hypersensibilité au principe actif des céphalosporines.
Mode of actions
La céfalexine se lie à une ou plusieurs protéines liant la pénicilline (PBP), ce qui inhibe la dernière étape de transpeptidation de la formation de peptidoglycane dans la paroi cellulaire bactérienne, interrompant la biosynthèse et provoquant la mort des cellules bactériennes.
Dosage & Administration
Adultes
1 à 4 g/jour en prises fractionnées. La dose habituelle est de 250 mg toutes les 6 heures.
Pharyngite streptococcique, infections de la peau et des structures cutanées, cystite simple chez les patients > 15 ans 500 mg toutes les 12 heures. Peut nécessiter des doses plus élevées pour des infections plus graves ou des organismes moins sensibles.
Enfants
25 à 50 mg/kg/jour en prises fractionnées. Pour la pharyngite streptococcique chez les patients âgés de plus d'un an et pour les infections de la peau et des structures cutanées, diviser la dose quotidienne totale et administrer toutes les 12 heures. En cas d'infections graves, doublez la dose.
Otite moyenne : 75 à 100 mg/kg/jour à diviser en 4 prises.
Infections à streptocoques bêta-hémolytiques : poursuivre le traitement pendant au moins 10 jours.
Insuffisance rénale :
ClCr (ml/min)
40-50 Max : 3 g par jour.
10-40 Max : 1,5 g par jour.
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
100ml Price : ৳81
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