A Fenac PLUS IM (Injection)
Manufactured by: Acme Laboratories Ltd.
Diclofenac + Lidocaine Hydrochloride Similar medicine
A Fenac PLUS IM is indicated for
- Rheumatoide Arthritis
- Osteoarthritis
- Morbus Bechterew
- Schmerzen
- akute Gicht
- Entzündung
- Tendinitis
- aktinische Keratosen
- Schleimbeutelentzündung
Precautions and warnings
Menschen mit einer Vorgeschichte von Magengeschwüren, Bluterbrechen, schwarzem Stuhl, Colitis ulcerosa, Asthma oder Asthma in der Vergangenheit, Morbus Crohn, Blutungsproblemen oder Bluterkrankungen müssen vorsichtig sein. Personen, die unter schweren Leber-, Herz- oder Nierenproblemen leiden, ältere Menschen sind oder derzeit oder in der Vergangenheit an Bluthochdruck leiden, sollten engmaschig überwacht werden. Wer über einen längeren Zeitraum NSAR (wie Diclofenac-Natrium) einnimmt, sollte sich regelmäßig untersuchen lassen, einschließlich Tests der Nieren-, Leber- und Blutfunktion. Wenn die Leberwerte abnormal bleiben, sich verschlimmern oder Symptome einer Lebererkrankung auftreten, sollte die Einnahme von Diclofenac-Natrium beendet werden.
Side-effects
- Die Nebenwirkungen von Diclofenac sind in der Regel mild und vorübergehend. Es wird im Allgemeinen gut vertragen. Zu Beginn der Behandlung klagen die Patienten jedoch manchmal über Magen-Darm-Beschwerden
- Oberbauchschmerzen
- Aufstoßen
- Übelkeit und Durchfall
- gelegentlich können auch Kopfschmerzen und Blutungen auftreten. Gelegentlich wurde über Hautausschlag
- periphere Ödeme und Anomalien der Serumtransaminase berichtet. Sehr selten berichtete Nebenwirkungen umfassen die Aktivierung von Magengeschwüren
- Hämatemesis oder Meläna sowie Blutdyskrasie (ausgiebige Anwendung). Es liegen vereinzelte Berichte über anaphylaktoide Reaktionen vor. Die Nebenwirkungen von Lidocain betreffen hauptsächlich das ZNS
- sind in der Regel von kurzer Dauer und dosisabhängig. Die ZNS-Reaktion kann sich in Schläfrigkeit
- Schwindel
- Orientierungslosigkeit
- Verwirrtheit
- Benommenheit usw. äußern. Bei der Anwendung von Augentropfen kann es bei 5–10 % der Patienten zu Augenbrennen oder allergischen Reaktionen kommen.
Drug Interactions
Diclofenac kann den Blutspiegel von Methotrexat erhöhen. Die gleichzeitige Einnahme mit anderen NSAIDs oder Blutverdünnern (wie Warfarin) erhöht das Risiko von Magen- und Darmblutungen. Das Risiko von Nierenproblemen ist bei gleichzeitiger Anwendung von Ciclosporin oder Triamteren höher. Bei Patienten mit einer schwerwiegenden bestehenden Hornhautentzündung kann die Anwendung von Diclofenac-Augentropfen zusammen mit Steroid-Augentropfen das Risiko einer Hornhautschädigung erhöhen. Colestyramin und Colestipol verringern die Menge an Diclofenac, die Ihr Körper aufnimmt. Die Einnahme von Diclofenac nach Sucralfat senkt dessen Blutspiegel. Diclofenac-Augentropfen können die Wirksamkeit von Acetylcholin- und Carbachol-Augentropfen beeinträchtigen. Diclofenac kann auch die Blutspiegel von Lithium und Digoxin erhöhen.
Der Diclofenac-Blutspiegel kann ansteigen, wenn er zusammen mit Cimetidin oder Propranolol eingenommen wird. Bei gleichzeitiger Einnahme von Betablockern oder anderen Arzneimitteln gegen Herzrhythmusstörungen besteht ein höheres Risiko für Herzprobleme. Die Gabe von Diclofenac zusammen mit intravenösem Phenytoin kann unerwünschte Auswirkungen auf das Herz verstärken. Ein niedriger Kaliumgehalt durch Medikamente wie Acetazolamid, Schleifendiuretika oder Thiazide kann die Wirkung von Lidocain beeinträchtigen. Wenn Sie Phenytoin oder andere enzyminduzierende Arzneimittel über einen längeren Zeitraum einnehmen, sind möglicherweise höhere Dosen erforderlich.
Contraindications
Dieses Medikament sollte nicht bei Patienten angewendet werden, die ein aktives oder vermutetes Magengeschwür, Magen-Darm-Blutungen haben oder in der Vergangenheit Asthma, Nesselsucht oder schwere Nasenallergien hatten, die durch Aspirin oder andere NSAIDs ausgelöst wurden.
Lidocain sollte nicht an Patienten verabreicht werden, bei denen eine Allergie gegen Lokalanästhetika vom Amidtyp bekannt ist.
Mode of actions
Diclofenac ist ein weit verbreitetes NSAID (nichtsteroidales entzündungshemmendes Medikament), das zur Gruppe der Phenylessigsäuren gehört. Es hilft, Entzündungen, Schmerzen und Fieber zu reduzieren. Es blockiert das Enzym Cyclooxygenase, das die Produktion von Substanzen (Prostaglandinen) verringert, die Entzündungen verursachen.
Lidocain ist ein Lokalanästhetikum vom Amidtyp. Es stabilisiert Nervenzellmembranen und blockiert Natriumionen, die für die Weiterleitung von Nervensignalen benötigt werden. Im Herzen verringert Lidocain abnormale elektrische Aktivität und automatische Signale in den Ventrikeln und im Reizleitungssystem (His-Purkinje-System) und verkürzt die Zeit, für die Herzzellen aktiviert werden.
Dosage & Administration
Erwachsene: Die Dosierung beträgt im Allgemeinen eine 75-mg-Ampulle täglich. In schweren Fällen (z. B. Koliken) kann die Tagesdosis ausnahmsweise auf zwei Ampullen zu 75 mg im Abstand von einigen Stunden erhöht werden.
Kinder: Bei juveniler chronischer Arthritis 1-3 mg Diclofenac-Natrium/kg Körpergewicht täglich in mehreren Dosen.
Ältere Patienten: Es wird die niedrigste wirksame Dosierung empfohlen, die dem Alter und dem körperlichen Zustand entspricht oder vom Arzt verordnet wird.
Pregnancy & Lactation
Dieses Arzneimittel ist während der Schwangerschaft nicht erlaubt. Verwenden Sie es nicht, wenn Sie schwanger sind. Es kann über die Haut und die Lunge aufgenommen werden und kann die Organe Ihres ungeborenen Kindes schädigen und zu angeborenen Behinderungen führen. Strenge wirksame Empfängnisverhütung während der Behandlung und für sechs Monate nach Absetzen dieses Arzneimittels. Wenn Sie schwanger werden, beenden Sie die Einnahme dieses Arzneimittels und sprechen Sie sofort mit Ihrem Arzt.
Es liegen keine spezifischen Informationen darüber vor, ob dieses Arzneimittel in die Muttermilch übergeht oder nicht. Angesichts der möglichen Risiken für die Kinder wird das Stillen während der Anwendung dieses Arzneimittels und mindestens zwei Wochen nach der letzten Dosis nicht empfohlen. Konsultieren Sie vor dem Stillen Ihren Arzt.
Pack Size & Price
10's pack Price : ৳140.6
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