Cofdil Surup (Syrup)
Manufactured by: Central Pharmaceutical Ltd.
Guaiphenesin + Pseudoephedrine Hydrochloride + Triprolidine Hydrochloride Similar medicine
Cofdil Surup is indicated for
- Neumonía
- Tos productiva
- Rinitis alérgica
- Estornudos
- Trastornos del tracto respiratorio
- Tos y secreción nasal
- Congestión nasal
Precautions and warnings
Puede provocar somnolencia y dificultar el buen desempeño en los exámenes de vigilancia auditiva. También podría afectar la capacidad del paciente para conducir y utilizar maquinaria. Como resultado, se debe evitar conducir y utilizar maquinaria durante el tratamiento con Aquaphen. Aunque no existen hechos objetivos, evite consumir alcohol u otros sedantes de acción central al mismo tiempo.
Los pacientes con hipertensión, enfermedades cardíacas, diabetes, hipertiroidismo, presión intraocular alta y agrandamiento prostático deben usarlo con precaución, al igual que con otros medicamentos simpaticomiméticos. A menos que lo indique un médico, no debe usarse para la tos persistente o crónica, como la causada por fumar, asma o enfisema, o tos acompañada de secreciones copiosas.
Side-effects
- Puede producirse depresión o excitación del sistema nervioso central (SNC). Se han informado alteraciones del sueño y
- raramente
- alucinaciones. Ocasionalmente se han notificado erupciones cutáneas
- taquicardia
- sequedad de boca
- nariz y garganta. Ocasionalmente se ha informado retención urinaria en hombres que reciben pseudoefedrina; el agrandamiento prostático podría haber sido un factor predisponente importante.
Drug Interactions
Los antihistamínicos aplicados sobre la piel, como la crema, ungüento o aerosol de difenhidramina, y los medicamentos para la presión arterial son algunos de los productos que pueden interactuar con este medicamento, especialmente guanetidina, metildopa, betabloqueantes como el atenolol o bloqueadores de los canales de calcio como la nifedipina.
Cuando se usan inhibidores de la MAO con este medicamento, puede ocurrir una interacción farmacológica significativa (potencialmente fatal). Durante el tratamiento con este medicamento, no tome inhibidores de la MAO (isocarboxazida, linezolid, metaxalona, azul de metileno, moclobemida, fenelzina, procarbazina, rasagilina, safinamida, selegilina, tranilcipromina). La mayoría de los inhibidores de la MAO deben evitarse durante dos semanas antes de iniciar este tratamiento. ¿Cuándo se debe empezar o dejar de tomar este medicamento? Consulte a su médico.
Si está tomando otros medicamentos que producen somnolencia, como analgésicos opioides (codeína, hidrocodona), alcohol, marihuana (cannabis), medicamentos para dormir o para la ansiedad (alprazolam, lorazepam, zolpidem), relajantes musculares (carisoprodol, ciclobenzaprina) u otros antihistamínicos, informe a su médico o farmacéutico (como cetirizina, difenhidramina).
Todos sus medicamentos (como los remedios para las alergias o la tos y el resfriado, así como los suplementos dietéticos) deben revisarse para detectar sustancias que puedan afectar su presión arterial o provocar somnolencia. Consulte con su farmacéutico sobre el uso seguro de ciertos productos.
Contraindications
Pacientes que previamente hayan dado positivo en guaifenesina, psedoefedrina o triprolidina. Dentro de las dos semanas posteriores a la interrupción del tratamiento con inhibidores de la monoaminooxidasa, este medicamento está contraindicado.
Los pacientes con hipertensión significativa o enfermedad de las arterias coronarias tienen un mayor riesgo.
Mode of actions
El clorhidrato de triprolidina es un antimuscarínico y un sedante suave que es un poderoso antagonista competitivo del receptor H1 de histamina.
La pseudoefedrina es un agonista de los receptores adrenérgicos y noradrenérgicos. Produce vasoconstricción al estimular directamente los receptores adrenérgicos de la mucosa respiratoria. También provoca relajación bronquial, aumento de la frecuencia cardíaca y contractilidad al estimular directamente los receptores adrenérgicos.
La guaifenesina es un expectorante para la tos productiva que aumenta el volumen y reduce la viscosidad del esputo tenaz.
Dosage & Administration
Adultos y Niños mayores de 12 años: 10 ml (2 cucharaditas) tres veces al día.
Niños de 6 a 12 años: 5 ml (1 cucharadita) tres veces al día.
Niños de 2 a 5 años: 2,5 ml (1/2 cucharadita) tres veces al día.
Pregnancy & Lactation
Aunque los estudios de reproducción en animales han demostrado un efecto adverso en el feto y no existen estudios adecuados y bien controlados en mujeres embarazadas, durante el embarazo este medicamento se puede utilizar sólo cuando sea definitivamente necesario a pesar de los riesgos potenciales.
Las madres con un bebé recién nacido que han usado este medicamento durante los últimos 3 meses de embarazo rara vez presentan síntomas que incluyen somnolencia, rigidez o temblores musculares, problemas para alimentarse o respirar, y llanto constante. Si nota alguno de estos síntomas en su bebé, especialmente durante el primer mes, informe al médico de inmediato.
Este medicamento pasa a la leche materna. Hable con su médico antes de amamantar.
Pack Size & Price
100ml bot Price : ৳50
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