Angilock PLUS 100/25 (Tablet)
Manufactured by: Square Pharmaceuticals Ltd.
Hydrochlorothiazide + Losartan Potassium Similar medicine
Angilock PLUS 100/25 is indicated for
- Hypertension
- Stroke risk reduction of hypertensive or LVH patients
Precautions and warnings
If you are allergic to losartan or hydrochlorothiazide, or if you have any additional allergies, tell your doctor before using this medication. Inactive chemicals may be included in this product, causing allergic reactions or other issues. For further information, speak with your pharmacist.
Tell your doctor if you have ever had gout, kidney disease, liver disease, lupus, dehydration, a high potassium level in your blood, or skin cancer before taking this medicine.
This medication has the potential to make you dizzy. You may become dizzy if you consume alcohol or cannabis. Do not drive, operate machinery, or engage in any other activity that requires attentiveness until you are sure you can do so safely. Limit your intake of alcoholic beverages. If you use cannabis, talk to your doctor.
Lightheadedness or dehydration can be exacerbated by excessive perspiration, diarrhea, or vomiting. Consult your doctor if you have persistent diarrhea or vomiting. Unless your doctor tells you otherwise, drink plenty of fluids to avoid dehydration.
This product may alter your blood sugar if you have diabetes. Check your blood sugar as prescribed and inform your doctor of the results. Your diabetic medication, exercise routine, or diet may need to be adjusted by your doctor.
This drug could make you more sun-sensitive. It may also raise your chance of skin cancer, especially if you use it for an extended period of time. Spend as little time as possible in the sun. Sunlamps and tanning booths should be avoided. When you're outside, use sunscreen and wear protective gear. If you get burnt, develop skin blisters/redness, or discover new or altered moles/skin lesions, call your doctor straight away.
Potassium levels may be affected by this product. Consult your doctor or pharmacist before taking potassium supplements or salt replacements that include potassium.
Side-effects
- Volume depletion
- electrolyte imbalance (especially hyperkalaemia); dry mouth
- thirst; lethargy
- drowsiness; muscle pain
- cramps; rashes
- photosensitivity
- thrombocytopenia
- jaundice
- pancreatitis; fatigue
- weakness; may precipitate an attack of gout; impotence; hyperglycaemia; anorexia
- nausea
- vomiting
- constipation
- diarrhoea; sialdenitis; raised urinary calcium concentration; headache
- dizziness; back pain
- myalgia; first-dose hypotension; angiodema; neutropenia; GI disturbances; transient elevation of liver enzymes; taste disturbances
- cough; exacerbation or activation of systemic lupus erythematous; palpitations; xanthopsia; leucopenia
- agranulocytosis
- aplastic anaemia; necrotising angiitis; glucosuria; renal dysfunction
- interstitial nephritis
- renal failure; migraine; hyponatraemia; UTI; chest pain; gastritis
- wt gain
- dyspepsia
- abdominal pain; bronchitis
- upper respiratory infection
- nasal congestion
- sinusitis; rise in cholesterol and/or triglycerides. Potentially Fatal: Hypersensitivity reactions; hemolytic anaemia; toxic epidermal necrolysis.
Drug Interactions
Drug interactions can cause your prescriptions to perform differently or put you at risk for dangerous adverse effects. This list does not include all potential medication interactions. Keep a list of everything you use including prescription and nonprescription pharmaceuticals, as well as herbal products and discuss it with your doctor and pharmacist. Without your doctor's permission, do not begin, stop, or modify the dosage of any medications.
Aliskiren, dofetilide, lithium, and medicines that raise potassium levels in the blood for example ACE inhibitors such as benazepril/lisinopril, birth control pills containing drospirenone are all possible interactions.
Some items contain substances that can elevate blood pressure or exacerbate heart failure. Tell your pharmacist about the products you're using and how to use them safely, especially cough and cold remedies, diet supplements, or NSAIDs like ibuprofen/naproxen.
Mode of actions
Hydrochlorothiazide enhances salt and chloride excretion in the kidneys while lowering the cardiac load. Losartan is an antihypertensive angiotensin II receptor (type AT1) antagonist that works by blocking angiotensin II's effects in the renin-angiotensin-aldosterone system. Angiotensin II's vasoconstrictor and aldosterone-secreting actions are selectively blocked by the medication and its active metabolite. In hypertension, the two medicines have a synergistic impact.
Dosage & Administration
Adult: PO Hypertension: Starting dose- Losartan 50 mg & Hydrochlorothiazide 12.50 mg once daily. Maximum dose- Losartan 100 mg & Hydrochlorothiazide 25 mg once daily.
Stroke risk reduction of hypertensive or LVH patients: Starting dose- Losartan 50 mg & Hydrochlorothiazide 12.5 mg once daily. Maximum dose- Losartan 100 mg followed by Hydrochlorothiazide 25 mg once daily.
Renal impairment: Dialysis patients: Avoid.
CrCl (ml/min)
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳360
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