Cardival Plus 160 (Tablet)
Manufactured by: Drug International Ltd.
Hydrochlorothiazide + Valsartan Similar medicine
Cardival Plus 160 is indicated for
- Hypertension
- Diabetic nephropathy
Precautions and warnings
For patients with diabetes mellitus or those who have had a sympathectomy, use with caution. This medication may make lupus (SLE) worse. Check blood potassium levels often. Watch out for symptoms of fluid or electrolyte problems. Stop this medicine before any parathyroid tests. It might affect your ability to drive or use machines. Be especially careful with elderly patients.
Side-effects
- Headache
- asthenia
- fatigue
- dizziness
- somnolence
- insomnia
- orthostatic hypotension
- paraesthesia
- nasopharyngitis
- tachycardia
- palpitations
- tinnitus
- vertigo
- dyspepsia
- diarrhoea
- flatulence
- dry mouth
- nausea
- vomiting
- abdominal pain
- peripheral oedema
- pyrexia
- increased BUN
- elevated LFT
- anxiety
- erectile dysfunction
- glucose intolerance
- increased serum cholesterol
- triglycerides
- uric acid. Electrolyte imbalances e.g. hypomagnesaemia
- hypercalcaemia
- hyponatraemia
- hypochloraemic alkalosis.
Drug Interactions
Taking valsartan with other blood pressure medications can make its effect stronger. If you use valsartan with potassium supplements, potassium-sparing diuretics, salt substitutes with potassium, or other drugs that affect potassium (such as heparin, ciclosporin, certain birth control pills, amphotericin, steroids, or carbenoxolone), your potassium levels may become too high, so you should have them checked often.
Taking NSAIDs (like ibuprofen or naproxen) with valsartan can make it less effective in lowering blood pressure and may raise the risk of kidney problems. Valsartan can also decrease how well your body gets rid of some chemotherapy drugs, such as cyclophosphamide or methotrexate. If you take vitamin D or calcium supplements, you could end up with high calcium levels.
**Serious risks:**
Valsartan can increase lithium levels, which can be dangerous, so your doctor should check your lithium levels regularly if you take both medicines. It can also increase the risk of a serious heart rhythm problem if taken with dofetilide, so you should not use these together.
Contraindications
Do not use this medicine if you are allergic to valsartan, hydrochlorothiazide, or sulfonamides. It should also not be used in people with severe liver problems or very poor kidney function.
Mode of actions
Valsartan lowers blood pressure by blocking the effects of a chemical called angiotensin II, which normally makes blood vessels tighten and causes the body to hold onto salt and water. Hydrochlorothiazide is a type of medicine called a diuretic, or “water pill,” that helps your body get rid of extra water and salt.
Dosage & Administration
Adult: PO : Initial: 80/12.5 mg once daily, up to 320/25 mg if needed.
Renal impairment:
CrCl (ml/min)
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
10's pack Price : ৳160
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