Dicaltrol .25mcg (Capsule)
Manufactured by: Drug International Ltd.
Calcitriol Similar medicine
Dicaltrol is indicated for
- 骨質疏鬆症、副甲狀腺功能低下、低血鈣、骨質軟化佝僂病、腎性骨營養不良、慢性腎透析。
Precautions and warnings
原因不明引起的高血鈣症。 兒童劑量必須根據特定兒童量身定制，並由醫生密切監測。 冠狀動脈疾病、腎衰竭和動脈硬化在老年人中都很常見。 副甲狀腺功能減退症。
由於過量的骨化三醇會導致高鈣血症，並且在極少數情況下會導致高鈣尿症，因此在治療早期應每週測量兩次血清鈣，同時調整劑量。
腎功能正常的骨化三醇使用者應避免脫水。 喝足夠的水很重要。
Side-effects
- 與骨化三醇治療相關的不良事件與維生素 D 攝取過量所遇到的不良事件類似，即高血鈣症或鈣中毒。 偶爾出現的急性症狀包括厭食、頭痛、噁心、嘔吐、腹痛或胃痛和便秘。
Drug Interactions
同時使用噻嗪類利尿劑治療會增加高血鈣的風險。 在接受洋地黃藥物治療的患者中，必須謹慎地確定骨化三醇的劑量，因為高血鈣症可能會導致心律不整。 高鎂血症可能是由含鎂藥物（例如抗酸劑）引起的。
Contraindications
高鈣血症，維生素 D 中毒的證據。 懷孕（劑量超過 RDA）。 一位母親給她的孩子餵母乳。
Mode of actions
骨化三醇透過促進腸道中的鈣吸收和腎臟中的保留來增加血清鈣濃度。 它還刺激腎小管中的磷酸鹽吸收，降低血清磷酸酶、PTH 和骨吸收。
Dosage & Administration
成人：膠囊：必須根據每位患者的血清鈣水平仔細確定骨化三醇的最佳每日劑量。 骨化三醇可以口服 0.25 mcg 或 0.50 mcg。
停經後骨質疏鬆症
建議劑量為 0.25 mcg，每日兩次或 0.50 mcg，每日一次。 應在 4 週、3 和 6 個月以及此後每隔 6 個月測定血清肌酸酐濃度。
腎性骨營養不良（透析患者）
骨化三醇的建議初始劑量為 0.25 mcg/天。 血清鈣濃度正常或僅輕微降低的患者可能對每隔一天服用 0.25 mcg 劑量的骨化三醇有反應。 大多數接受血液透析的患者對每天 0.5 至 1 微克的劑量有反應。
副甲狀腺功能減退症和佝僂病
骨化三醇的建議初始劑量為 0.25 mcg/天，早上服用。 如果沒有觀察到滿意的反應，可以每隔 2 至 4 週增加劑量。
透析前患者：
成人和 3 歲及以上兒童患者骨化三醇的建議初始劑量為 0.25 mcg/天。 如有必要，該劑量可增加至 0.5 mcg/天。
兒童劑量：1個月至3歲，骨化三醇的建議初始劑量為10至15奈克/公斤/天。
注射
根據低血鈣和/或繼發性副甲狀腺功能亢進的嚴重程度，骨化三醇注射的建議靜脈初始劑量為 1 mcg (0.02 mcg/kg) 至 2 mcg，每週 3 次，大約每隔一天注射一次。 小至 0.5 mcg 和大至 4 mcg 的劑量每週三次，已被用作初始劑量。 若未觀察到滿意的反應，劑量可每隔 2 至 4 週增加 0.5 至 1 mcg。
Pregnancy & Lactation
儘管動物生殖研究顯示對胎兒有不良影響，並且在孕婦中沒有充分且良好對照的研究，但在懷孕期間，儘管存在潛在風險，但在確實需要時可以使用該藥物。
在懷孕最後 3 個月內使用這種藥物的新生兒母親可能很少會出現困倦、肌肉僵硬或顫抖、餵食或呼吸困難、持續哭泣等症狀。 如果您發現寶寶有任何這些症狀，尤其是在第一個月內，請立即告訴醫生。
這種藥物會進入母乳。 哺乳前請先諮詢您的醫生。
Pack Size & Price
0.25mcg x 50'spack Price : ৳350
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