Giran H (Tablet)
Manufactured by: Aristopharma Limited
Candesartan Cilexetil + Hydrochlorothiazide Similar medicine
Giran H is indicated for
- Hypertension
- Congestive heart failure
Precautions and warnings
People who have low blood volume, low sodium, kidney problems, or certain heart conditions (like narrowed aortic or mitral valves, or hypertrophic obstructive cardiomyopathy), as well as those with renal artery stenosis or primary hyperaldosteronism, should use caution. Patients with a history of angioedema or urticaria should also be careful. It’s important to regularly check blood potassium levels, especially for elderly people or those with kidney problems. During major surgery or anesthesia, low blood pressure may happen because the renin-angiotensin system is suppressed.
Side-effects
- Dizziness
- headache
- vertigo
- depression
- somnolence
- fever
- back pain
- upper respiratory tract infections
- 1st dose orthostatic hypotension
- rash
- diarrhoea
- decreased haemoglobin
- renal impairment
- hepatitis.
Drug Interactions
NSAIDs can make blood pressure medicines less effective and may cause kidney problems, possibly even sudden kidney failure. They can also raise lithium levels in the blood. Using NSAIDs with potassium-sparing diuretics, potassium supplements, or potassium-based salt substitutes may lead to high potassium levels.
Serious Warning: Taking NSAIDs together with aliskiren if you have diabetes may increase the risk of kidney damage, low blood pressure, and high potassium levels.
Contraindications
Do not use if you are allergic to it. Avoid during the second and third trimesters of pregnancy and while breastfeeding.
Mode of actions
Candesartan works by blocking angiotensin II from attaching to AT1 receptors found in tissues like blood vessels and the adrenal gland. This stops blood vessels from narrowing and reduces the release of aldosterone.
Hydrochlorothiazide prevents sodium and chloride from being reabsorbed in the kidney's distal tubules. As a result, more sodium, water, potassium, and hydrogen ions are removed from the body in urine.
Dosage & Administration
Adult: PO HTN Initial: 8 mg once daily.Max: 32 mg/day. Heart failure Initial: 4 mg once daily. May double dose at intervals of not
Pregnancy & Lactation
This medicine is not allowed during pregnancy. Do not use it if you are pregnant. It can be absorbed through the skin and lungs caused can damage your unborn child’s organs and cause congenital disabilities. Strict effective birth control during treatment and for six months after stopping this medicine. If you do become pregnant, stop taking this medicine and discuss your doctor right away.
There is no specific information on whether this medicine passes into breast milk or not. Considering the possible risks for the children, breastfeeding while using this medicine is not recommended and at least two weeks after the last dose. Consult your doctor before breastfeeding.
Pack Size & Price
30's pack Price : ৳180
Similar medicine
Manufactured by: Aristopharma Limited
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There are few similar medicines of Giran H are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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