Loracef 125mg/1.2ml (Paediatric Drops)
Manufactured by: Square Pharmaceuticals Ltd.
Cefaclor Similar medicine
Loracef is indicated for
- Pneumonie
- méningite
- péritonite
- otite moyenne
- septicémie
- infections des voies biliaires
- infections des voies urinaires
- infections de la peau et des structures cutanées
- infections des voies respiratoires supérieures et inférieures
- pharyngite et amygdalite.
Precautions and warnings
Informez votre médecin ou votre pharmacien de vos antécédents médicaux, en particulier si vous souffrez d'une maladie rénale ou intestinale, avant d'utiliser ce médicament.
Le céfaclor peut altérer l'efficacité des vaccinations bactériennes vivantes telles que le vaccin contre la typhoïde. Avant de vous faire vacciner ou vacciner, informez votre médecin que vous prenez du céfaclor.
Side-effects
- Réactions allergiques ; diarrhée
- nausées
- vomissements ; candidose
- éosinophilie; transaminases élevées. Potentiellement mortel : réaction anaphylactique ; colite pseudomembraneuse.
Drug Interactions
L'impact néphrotoxique des aminoglycosides peut être amplifié. Le BCG, la vaccination contre la typhoïde et le picosulfate de Na peuvent avoir une efficacité thérapeutique réduite. L'utilisation concomitante avec la warfarine peut entraîner une augmentation du temps de Quick. L'excrétion du céfaclor est inhibée par le probénécide.
Mode of actions
Le céfaclor se lie à une ou plusieurs protéines liant la pénicilline (PBP), ce qui inhibe la dernière étape de transpeptidation de la production de peptidoglycane dans la paroi cellulaire bactérienne, interrompant la biosynthèse et provoquant la mort des cellules bactériennes. E. coli, S. pneumoniae, N. gonorrhoeae, P. mirabilis et H. influenzae font partie des bactéries gm-ve qu'il tue.
Dosage & Administration
Orale
Infections des voies urinaires, Infections des voies respiratoires supérieures et inférieures, Infections cutanées, Otite moyenne
Adulte : Sous forme monohydratée : 250 à 500 mg toutes les 8 heures. Max : 4 g par jour.
Enfant : > 1 mois : 20 mg/kg par jour à diviser en 3 prises, augmenté à 40 mg/kg par jour si nécessaire, 5 ans : 250 mg tid.
Suspensions et gouttes pédiatriques :
1 mois à 1 an 2,5 ml t.i.d. 0,625 ml trois fois par jour
1 an à 5 ans 5 ml t.i.d. 1,25 ml trois fois par jour
plus de 5 ans 10 ml trois fois par jour 2,5 ml trois fois par jour
Pregnancy & Lactation
Bien que les études sur la reproduction animale aient montré un effet indésirable, même parfois sans pouvoir démontrer le risque pour le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste en cas de nécessité absolue.
Discutez avec vos médecins et faites-leur part de vos commentaires sur ce médicament.
Il n'existe aucune information spécifique indiquant si ce médicament est transmis au bébé par le lait maternel. Discutez-en avec votre médecin avant d'allaiter.
Pack Size & Price
15ml Price : ৳125.47
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Manufactured by: Square Pharmaceuticals Ltd.
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