Exovate N (Cream)
Manufactured by: Beximco Pharmaceuticals Ltd.
Clobetasol Propionate 0.05% + Neomycin Sulphate 0.5% + Nystatin BP 1,00,000 IU. Similar medicine
Exovate N is indicated for
- Psoriasis
- eczéma
- troubles inflammatoires sévères de la peau
Precautions and warnings
Il est préférable d’éviter d’utiliser des traitements topiques pendant une longue période, surtout chez les nourrissons et les enfants, car ils peuvent facilement causer des problèmes au niveau des glandes surrénales, même si la peau n’est pas couverte. Si ces traitements sont nécessaires chez les enfants ou sur le visage, utilisez-les uniquement pendant 5 jours maximum et ne couvrez pas la zone. Faites attention à ne pas mettre le médicament dans les yeux lorsque vous l'appliquez sur les paupières. Une surveillance étroite est importante si le traitement concerne le psoriasis. Pour les traitements du cuir chevelu, gardez le produit éloigné des yeux. Il est inflammable, alors n'utilisez pas et ne séchez pas vos cheveux à proximité de flammes nues ou d'incendies.
Side-effects
- Dermatite périorale
- stries surtout dans les flexions. Atrophie cutanée et épidermique
- surtout sur le visage
- purpura stéroïdien. Potentiellement mortel : l'utilisation prolongée d'une grande quantité de propionate de clobétasol peut conduire à des niveaux systémiques suffisants pour produire une suppression surrénalienne
- le syndrome de Cushing
- le diabète et l'hypertension.
Drug Interactions
Si une quantité importante de néomycine est absorbée dans le corps, les effets de suppression respiratoire des bloqueurs neuromusculaires peuvent durer plus longtemps et devenir plus forts.
Contraindications
Enfant
Mode of actions
Le clobétasol est un stéroïde puissant utilisé sur la peau pour réduire l'inflammation. Il agit en rétrécissant les vaisseaux sanguins et en réduisant la production de collagène. La néomycine est un antibiotique qui tue certaines bactéries en se fixant à des parties de leurs cellules appelées ribosomes, ce qui les empêche de fabriquer des protéines et les amène à commettre des erreurs lors de la lecture des instructions génétiques. La nystatine traite les infections fongiques en se fixant à une substance présente dans la membrane cellulaire du champignon appelée ergostérol. Cela provoque des fuites dans la paroi cellulaire, entraînant la perte d'un contenu cellulaire important par le champignon.
Dosage & Administration
Adultes et enfants de plus de 2 ans :
Appliquer avec parcimonie sur la zone affectée une à deux fois par jour jusqu'à amélioration. Comme avec d'autres préparations topiques stéroïdes hautement actives, le traitement doit être interrompu lorsque le contrôle est atteint.
Le traitement ne doit pas être poursuivi plus de 7 jours sans surveillance médicale. Si une cure plus longue est nécessaire, il est recommandé de ne pas poursuivre le traitement plus de 4 semaines sans que l'état du patient soit réexaminé.
Personnes âgées : Cette préparation convient aux personnes âgées. Des précautions doivent être prises dans les cas où une diminution de la fonction rénale existe et où une absorption systémique significative du sulfate de néomycine peut se produire.
Enfants : De moins de 2 ans cette préparation est déconseillée.
Pregnancy & Lactation
Bien que des études sur la reproduction animale aient montré un effet indésirable sur le fœtus et qu'il n'existe pas d'études adéquates et bien contrôlées chez la femme enceinte, ce médicament peut être utilisé pendant la grossesse juste lorsque cela est absolument nécessaire, malgré les risques potentiels.
Les mères d'un nouveau-né qui ont utilisé ce médicament au cours des 3 derniers mois de leur grossesse peuvent rarement créer des symptômes tels que somnolence, raideur ou tremblements musculaires, troubles de l'alimentation ou de la respiration, pleurs constants. Si vous remarquez l'un de ces symptômes chez votre bébé, en particulier au cours de son premier mois, informez-en immédiatement le médecin.
Ce médicament passe dans le lait maternel. Parlez-en à votre médecin avant d'allaiter.
Pack Size & Price
25gm tube Price : ৳75
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