Exovate N (Cream)
Manufactured by: Beximco Pharmaceuticals Ltd.
Clobetasol Propionate 0.05% + Neomycin Sulphate 0.5% + Nystatin BP 1,00,000 IU. Similar medicine
Exovate N is indicated for
- Psoriasis
- Eksim
- Kelainan kulit inflamasi yang parah
Precautions and warnings
Sebaiknya hindari penggunaan pengobatan topikal dalam jangka waktu lama, terutama pada bayi dan anak-anak, karena dapat dengan mudah menyebabkan masalah pada kelenjar adrenal, meskipun kulit tidak tertutupi. Jika perawatan ini diperlukan pada anak-anak atau pada wajah, gunakan hanya hingga 5 hari dan jangan menutupi area tersebut. Hati-hati jangan sampai obat mengenai mata saat mengoleskannya pada kelopak mata. Pengawasan ketat penting jika pengobatannya untuk psoriasis. Untuk perawatan kulit kepala, jauhkan produk dari mata. Bahan ini mudah terbakar, jadi jangan gunakan atau keringkan rambut Anda di dekat api terbuka atau perapian.
Side-effects
- Dermatitis perioral
- striae terutama pada lipatan. Atrofi dermal dan epidermal terutama pada wajah
- purpura steroid. Berpotensi Fatal: Penggunaan clobetasol propionate dalam jumlah besar dalam waktu lama dapat menyebabkan tingkat sistemik yang cukup untuk menghasilkan penekanan adrenal
- sindrom Cushing
- diabetes dan hipertensi.
Drug Interactions
Jika sejumlah besar neomisin diserap ke dalam tubuh, hal ini dapat membuat efek penghambat neuromuskular yang menekan pernapasan bertahan lebih lama dan menjadi lebih kuat.
Contraindications
Anak
Mode of actions
Clobetasol adalah obat steroid kuat yang digunakan pada kulit untuk mengurangi peradangan. Ia bekerja dengan mempersempit pembuluh darah dan menurunkan produksi kolagen. Neomycin adalah antibiotik yang membunuh bakteri tertentu dengan menempel pada bagian selnya yang disebut ribosom, sehingga menghentikan pembuatan protein dan menyebabkan kesalahan saat membaca instruksi genetik. Nystatin mengobati infeksi jamur dengan menempel pada zat di membran sel jamur yang disebut ergosterol. Hal ini membuat dinding sel bocor sehingga menyebabkan jamur kehilangan kandungan penting selnya.
Dosage & Administration
Dewasa dan anak di atas 2 tahun:
Oleskan secukupnya pada area yang terkena sekali atau dua kali sehari sampai terjadi perbaikan. Seperti halnya dengan sediaan steroid topikal lain yang sangat aktif, terapi harus dihentikan ketika kontrol telah tercapai.
Pengobatan tidak boleh dilanjutkan lebih dari 7 hari tanpa pengawasan medis. Jika diperlukan pengobatan yang lebih lama, dianjurkan agar pengobatan tidak dilanjutkan lebih dari 4 minggu tanpa meninjau kondisi pasien.
Lansia: Sediaan ini cocok digunakan pada orang lanjut usia. Perhatian harus dilakukan jika terjadi penurunan fungsi ginjal dan penyerapan sistemik Neomycin Sulphate yang signifikan dapat terjadi.
Anak-anak: Di bawah 2 tahun persiapan ini tidak dianjurkan.
Pregnancy & Lactation
Meskipun penelitian pada reproduksi hewan menunjukkan efek buruk pada janin dan belum ada penelitian yang memadai dan terkontrol dengan baik pada wanita hamil, namun selama kehamilan, obat ini dapat digunakan tepat ketika benar-benar diperlukan meskipun ada potensi risikonya.
Ibu dengan bayi baru lahir yang telah menggunakan obat ini selama 3 bulan terakhir kehamilan mungkin jarang mengalami gejala termasuk mengantuk, otot kaku atau gemetar, kesulitan makan atau bernapas, dan menangis terus-menerus. Jika Anda melihat gejala-gejala ini pada bayi Anda terutama pada bulan pertama, segera beri tahu dokter.
Obat ini masuk ke dalam ASI. Bicaralah dengan dokter Anda sebelum menyusui.
Pack Size & Price
25gm tube Price : ৳75
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