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Kolosal IV (Infusion)

Manufactured by: Popular Pharmaceuticals Ltd.

Potassium Chloride 0.1% + Sodium Acetate 0.65% + Sodium Chloride 0.5% Similar medicine

Kolosal IV is indicated for

  • Diarrhea
  • Dehydration
  • Cholera
  • Vomiting
  • Fluid
  • electrolyte loss

Precautions and warnings

This solution should not be given quickly or for a long time. Because it contains different electrolytes, it should be used carefully in people who could be harmed by changes in electrolyte levels. This includes people who are pregnant, have kidney problems, heart failure, fluid in the lungs, or are taking potassium-sparing diuretics.

Drug Interactions

**Potassium Chloride**:
Some medicines can increase potassium levels in your body, such as potassium-sparing diuretics, ACE inhibitors, ciclosporin, and other drugs that contain potassium. Medicines known as antimuscarinics can slow down how quickly your stomach empties, which raises the chance of stomach side effects, especially with solid pills.

**Sodium Chloride**:
Sodium chloride can change the levels of lithium in your blood.

**Sodium Acetate**:
Sodium acetate can affect how your body absorbs some medicines because it raises the stomach’s pH. It may also help your kidneys get rid of acidic drugs like salicylates and barbiturates faster, while making basic drugs stay in your body longer.

Contraindications

Do not use this medication if you have kidney failure that causes very little urine (oliguria) or if your kidneys are not producing any urine at all (anuria).

Mode of actions

**Sodium** helps control the amount and distribution of water in the body. It is the main positive ion (cation) in fluid outside the cells, making up more than 90% of such ions. The acetate part can be turned into bicarbonate in the liver, which helps balance the body’s acids and bases.

**Potassium chloride** is the main cation inside our cells. It is essential for sending nerve signals in the heart, brain, and muscles. Potassium also helps muscles contract (including the heart), supports healthy kidney function, keeps acid-base balance, helps with carbohydrate use, and aids in stomach acid production.

**Sodium chloride** is the main extracellular cation and is important for keeping electrolytes and fluids balanced in the body. It helps control fluid pressure and proper water distribution by replacing sodium. Sodium chloride is used to provide fluids and electrolytes, treat metabolic acidosis, as a priming solution in dialysis, and to manage high blood sugar in hyperosmolar diabetes. It is also used to dilute other drugs for infusions.

Dosage & Administration

According to the requirements or as advised by the physician.The volume and rate of infusion will depend upon the requirements of the patients and the judgement of the physician.

It usually varies with age, weight and clinical condition of the patient. The recommended flow rate is up to 100-drops/minute/70 kg body weight.

Pregnancy & Lactation

FDA has not yet classified this medicine into a specified pregnancy category. Although there is no enough evidence that taking this medicine during you are pregnant is harmful.

Discuss with your doctor if you are trying to get pregnant while taking this medicine too.

If you do become pregnant while you are taking this medicine, you should continue to take it and contact with your doctors as quickly as possible. They can assist you to decide whether or not to keep taking this medicine. If you abandon taking this medicine and become sick, this would be more pernicious to your child than staying on the medication.


There is no specific information about whether this medicine is passed on to the baby through breast milk. During this medication, if your baby becomes very sleepy, restless, fatigued, exhibit feeding problems, stop breastfeeding and talk to your doctors very quickly.

Pack Size & Price

500 ml bag / 1000 ml bag Price : ৳52.80 / 66

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There are few similar medicines of Kolosal IV are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.

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