Rasilez 150mg (Tablet)
Manufactured by: Novartis Farma SpA, Italy
Aliskiren Similar medicine
Rasilez is indicated for
- Hipertensión
Precautions and warnings
ICC grave, depleción de sodio o depleción de volumen. Si la diarrea es intensa y persistente, deje de tomarlo. Lactancia. Parámetros a controlar Controlar periódicamente los niveles séricos de potasio y la función renal.
Side-effects
- Diarrea
- dispepsia
- ERGE
- dolor abdominal
- hipotensión
- dolor de cabeza
- fatiga
- mareos
- dolor de espalda
- tos
- erupciones cutáneas
- hiperuricemia
- gota
- cálculos renales
- hiperpotasemia
- descenso de los niveles de Hb (relacionado con la dosis)
- angioedema y convulsiones. Potencialmente fatal: reacciones anafilácticas.
Drug Interactions
Junto con otros antihipertensivos, existe un mayor riesgo de hipotensión. Los inhibidores de la ECA, los antagonistas de los receptores de angiotensina II y los fármacos antiinflamatorios no esteroides aumentan el riesgo de insuficiencia renal aguda. Con los AINE, el efecto antihipertensivo puede verse disminuido. La atorvastatina, el itraconazol, el ketoconazol y el verapamilo aumentaron los niveles séricos. Las concentraciones de furosemida y aliskiren disminuyeron significativamente. Con diuréticos ahorradores de potasio, suplementos de potasio o cualquier otro agente que pueda elevar los niveles séricos de potasio, existe un mayor riesgo de hiperpotasemia.
Con los inhibidores de la ECA o los antagonistas de los receptores de angiotensina II, existe un mayor riesgo de insuficiencia renal, hipotensión e hiperpotasemia. Concentración plasmática notablemente aumentada con ciclosporina, itraconazol y quinidina.
Contraindications
historia de angioedema; Insuficiencia renal significativa En pacientes con diabetes e insuficiencia renal (TFG), se recomienda el uso concomitante de inhibidores de la ECA o antagonistas de los receptores de angiotensina II.
Mode of actions
Aliskiren es un inhibidor directo de la renina no peptídico, activo por vía oral, potente y específico que se utiliza para tratar la hipertensión arterial. Bloquea la conversión de angiotensinógeno en angiotensina I y, por tanto, la síntesis posterior de angiotensina II y aldosterona mediante el bloqueo de la enzima renina. El tratamiento con aliskiren reduce la actividad de la renina plasmática y las concentraciones de angiotensina I, angiotensina II y aldosterona, a diferencia de los inhibidores de la ECA y los antagonistas de los receptores de angiotensina II, que promueven un aumento compensatorio en la actividad de la renina plasmática.
Dosage & Administration
orales
Hipertensión esencial
Adultos: >18 años 150 mg una vez al día, aumentado a 300 mg una vez al día si es necesario.
Ancianos: No es necesario ajustar la dosis.
Insuficiencia hepática: No es necesario ajustar la dosis.
Pregnancy & Lactation
Este medicamento no está permitido durante el embarazo. No lo utilice si está embarazada. Puede absorberse a través de la piel y los pulmones y puede dañar los órganos del feto y causar discapacidades congénitas. Control de la natalidad estricto y eficaz durante el tratamiento y durante seis meses después de suspender este medicamento. Si queda embarazada, deje de tomar este medicamento y hable con su médico de inmediato.
No existe información específica sobre si este medicamento pasa a la leche materna o no. Teniendo en cuenta los posibles riesgos para los niños, no se recomienda amamantar mientras se utiliza este medicamento y al menos dos semanas después de la última dosis. Consulte a su médico antes de amamantar.
Pack Size & Price
7's pack Price : ৳546
Similar medicine
Manufactured by: Novartis Farma SpA, Italy
Manufactured by: Novartis Farma SpA, Italy
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There are few similar medicines of Rasilez are manufactured by other companies using the same ingredients. Although, it would be good if you are able to use the same medicine, which has been prescribed by your Doctor. Due to availability in the local market, you can try others. Please make sure and contact your Doctor first about alternatives.
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